Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction

Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction

2-Ethylhexyl diphenyl phosphate (EHDPP) is one of the typical organophosphate flame retardants (OPFRs) and has been widely detected in environmental media. Exposure to EHDPP during pregnancy affects placental development and fetal growth. Liver X receptor α (LXRα) is essential to placental developme...

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Bibliographic Details
Main Authors: Yue Zhang, Jie Liang, Hao Gu, Ting Du, Pengfei Xu, Ting Yu, Qing He, Zhenyao Huang, Saifei Lei, Jing Li
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
2-Ethylhexyl diphenyl phosphate
LXRα
Placenta toxicity
Cell migration
Angiogenesis
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323011090

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