Synthesis and Biological Evaluation of New 2-Azetidinones with Sulfonamide Structures

Synthesis and Biological Evaluation of New 2-Azetidinones with Sulfonamide Structures

New series of N-(arylidene)hydrazinoacetyl sulfonamides 4a1–6, 4b1–6 and N-(4-aryl-3-chloro-2-oxoazetidin-1-yl)aminoacetyl sulfonamides 5a1–6, 5b1–6 were synthesized. The structures of the new derivatives was confirmed using spectral methods (FT-IR, 1H-NMR, 13C-NMR). The antibacterial activities of...

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Bibliographic Details
Main Authors: Dragos Pieptu, Ramona Florina Moraru, Valentin Nastasa, Mihai Mares, Cornelia Vasile, Florentina Lupascu, Oana Maria Dragostin, Lenuta Profire
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Molecules
Subjects:
sulfonamide
azetidinone
synthesis
antimicrobial activity
antioxidant effect
Online Access:http://www.mdpi.com/1420-3049/18/4/4140

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