Argininyl-fructosyl-glucose (AFG) antagonizes D-galactose-induced cellular senescence of neuro-2a via inhibiting endoplasmic reticulum stress and apoptosis

Argininyl-fructosyl-glucose (AFG) antagonizes D-galactose-induced cellular senescence of neuro-2a via inhibiting endoplasmic reticulum stress and apoptosis

Argininyl-fructosyl-glucose (AFG), a distinctive non-saponin compound isolated from red ginseng (Panax ginseng. C.A. Meyer), demonstrates neuroprotective effects. However, the molecular mechanism underlying AFG's anti-aging properties remains unclear. This study established an in vitro D-galact...

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Bibliographic Details
Main Authors: Shan Tang, Yun-yi Hou, Rui-yi Hu, Jun-jie Zhang, Xu-fei Gao, Ming Zhang, Zi Wang, Rui Zhang, Pin-hui Jia, Wei Li
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Functional Foods
Subjects:
Argininyl-fructosyl-glucose
Ginseng
D-galactose, N2a cell
Senescence
Endoplasmic reticulum stress
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S175646462400104X

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