Dietary shochu kasu alleviates fatty liver induced by orotic acid
The effects of dietary shochu kasu (5%) on orotic acid-induced fatty liver were studied in rats. Liver triglyceride content of orotic acid-fed rats increased by 5-fold in comparison to basal group. Shochu kasu reduced triglyceride content by two-third. The activities of fatty acid synthase and pho...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bangladesh Pharmacological Society
2010-09-01
|
| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/5921 |
| _version_ | 1819028043637719040 |
|---|---|
| author | Yohanes Buang Pius D. Ola Teruyoshi Yanagita |
| author_facet | Yohanes Buang Pius D. Ola Teruyoshi Yanagita |
| author_sort | Yohanes Buang |
| collection | DOAJ |
| description | The effects of dietary shochu kasu (5%) on orotic acid-induced fatty liver were studied in rats. Liver triglyceride content of orotic acid-fed rats increased by 5-fold in comparison to basal group. Shochu kasu reduced triglyceride content by two-third. The activities of fatty acid synthase and phosphatidate phosphohydrolase significantly decreased that was approximately by 35% and 20%, respectively. The serum lipid levels however were nearly unchanged. The alleviation of fatty liver in rats with shochu kasu, therefore, was associated with the inhibition of fatty acid synthase and phosphatidate phosphohydrolase activities. |
| first_indexed | 2024-12-21T05:52:06Z |
| format | Article |
| id | doaj.art-a61acd15ffea4b87b25b10e3005e7c89 |
| institution | Directory Open Access Journal |
| issn | 1991-0088 |
| language | English |
| last_indexed | 2024-12-21T05:52:06Z |
| publishDate | 2010-09-01 |
| publisher | Bangladesh Pharmacological Society |
| record_format | Article |
| series | Bangladesh Journal of Pharmacology |
| spelling | doaj.art-a61acd15ffea4b87b25b10e3005e7c892022-12-21T19:13:56ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882010-09-015110.3329/bjp.v5i1.5921Dietary shochu kasu alleviates fatty liver induced by orotic acidYohanes Buang0Pius D. Ola1Teruyoshi Yanagita2Department of Chemistry, Faculty of Science and Engineering, Nusa Cendana University-IndonesiaDepartment of Chemistry, Faculty of Science and Engineering, Nusa Cendana University, KupangLaboratory of Applied Biochemistry, Department of Applied Biological Science, Saga UniversityThe effects of dietary shochu kasu (5%) on orotic acid-induced fatty liver were studied in rats. Liver triglyceride content of orotic acid-fed rats increased by 5-fold in comparison to basal group. Shochu kasu reduced triglyceride content by two-third. The activities of fatty acid synthase and phosphatidate phosphohydrolase significantly decreased that was approximately by 35% and 20%, respectively. The serum lipid levels however were nearly unchanged. The alleviation of fatty liver in rats with shochu kasu, therefore, was associated with the inhibition of fatty acid synthase and phosphatidate phosphohydrolase activities.https://www.banglajol.info/index.php/BJP/article/view/5921Fatty liverOrotic acidTriacylglycerolShochu kasu |
| spellingShingle | Yohanes Buang Pius D. Ola Teruyoshi Yanagita Dietary shochu kasu alleviates fatty liver induced by orotic acid Bangladesh Journal of Pharmacology Fatty liver Orotic acid Triacylglycerol Shochu kasu |
| title | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_full | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_fullStr | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_full_unstemmed | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_short | Dietary shochu kasu alleviates fatty liver induced by orotic acid |
| title_sort | dietary shochu kasu alleviates fatty liver induced by orotic acid |
| topic | Fatty liver Orotic acid Triacylglycerol Shochu kasu |
| url | https://www.banglajol.info/index.php/BJP/article/view/5921 |
| work_keys_str_mv | AT yohanesbuang dietaryshochukasualleviatesfattyliverinducedbyoroticacid AT piusdola dietaryshochukasualleviatesfattyliverinducedbyoroticacid AT teruyoshiyanagita dietaryshochukasualleviatesfattyliverinducedbyoroticacid |