Allele-specific amplification in cancer revealed by SNP array analysis.

Allele-specific amplification in cancer revealed by SNP array analysis.

Amplification, deletion, and loss of heterozygosity of genomic DNA are hallmarks of cancer. In recent years a variety of studies have emerged measuring total chromosomal copy number at increasingly high resolution. Similarly, loss-of-heterozygosity events have been finely mapped using high-throughpu...

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Bibliographic Details
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2005-11-01
Series:	PLoS Computational Biology
Online Access:	http://dx.doi.org/10.1371/journal.pcbi.0010065

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