Effects of the interaction of Notch and TLR4 pathways on inflammation and heart function in septic heart

Effects of the interaction of Notch and TLR4 pathways on inflammation and heart function in septic heart

We investigated the role of the interaction between the Notch and Toll-like receptor 4 (TLR4) pathways in septic myocardial injury. The sepsis model was induced in rats with lipopolysaccharide (LPS). Rats were divided into control, LPS, LPS + TAK242 ((6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cycl...

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Bibliographic Details
Main Authors: Liu Ziyang, Li Wenli, Cao Yang, Zhang Xiaoxia, Yang Kai, Yin Fukang, Yang Meng, Peng Peng
Format: Article
Language:English
Published: De Gruyter 2022-07-01
Series:Open Life Sciences
Subjects:
sepsis
myocardial injury
tlr4
notch
nf-κb
Online Access:https://doi.org/10.1515/biol-2022-0076

Internet

https://doi.org/10.1515/biol-2022-0076

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