Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.
Mast cells play a central role in both innate and acquired immunity. When activated by IgE-dependent FcεRI cross-linking, mast cells rapidly initiate a signaling cascade and undergo an extensive release of their granule contents, including inflammatory mediators. Some SNARE (soluble N-ethylmaleimide...
Autores principales: | Zhengli Wu, Adam J MacNeil, Jason N Berman, Tong-Jun Lin |
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Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Public Library of Science (PLoS)
2013-01-01
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Colección: | PLoS ONE |
Acceso en línea: | http://europepmc.org/articles/PMC3590206?pdf=render |
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