Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides
A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2013-04-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/18/4/4403 |
| _version_ | 1828329541349670912 |
|---|---|
| author | Wing-Yiu Yu Chun-Wo Chan Wing-Nga Sit |
| author_facet | Wing-Yiu Yu Chun-Wo Chan Wing-Nga Sit |
| author_sort | Wing-Yiu Yu |
| collection | DOAJ |
| description | A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield. |
| first_indexed | 2024-04-13T20:26:48Z |
| format | Article |
| id | doaj.art-a622fe8583d9469eb0117d0227dda8da |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-13T20:26:48Z |
| publishDate | 2013-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-a622fe8583d9469eb0117d0227dda8da2022-12-22T02:31:18ZengMDPI AGMolecules1420-30492013-04-011844403441810.3390/molecules18044403Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl AcylperoxidesWing-Yiu YuChun-Wo ChanWing-Nga SitA palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.http://www.mdpi.com/1420-3049/18/4/4403C–H bondoxidationpalladium |
| spellingShingle | Wing-Yiu Yu Chun-Wo Chan Wing-Nga Sit Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides Molecules C–H bond oxidation palladium |
| title | Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides |
| title_full | Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides |
| title_fullStr | Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides |
| title_full_unstemmed | Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides |
| title_short | Palladium(II)-Catalyzed othro-C–H-Benzoxylation of 2-Arylpyridines by Oxidative Coupling with Aryl Acylperoxides |
| title_sort | palladium ii catalyzed othro c h benzoxylation of 2 arylpyridines by oxidative coupling with aryl acylperoxides |
| topic | C–H bond oxidation palladium |
| url | http://www.mdpi.com/1420-3049/18/4/4403 |
| work_keys_str_mv | AT wingyiuyu palladiumiicatalyzedothrochbenzoxylationof2arylpyridinesbyoxidativecouplingwitharylacylperoxides AT chunwochan palladiumiicatalyzedothrochbenzoxylationof2arylpyridinesbyoxidativecouplingwitharylacylperoxides AT wingngasit palladiumiicatalyzedothrochbenzoxylationof2arylpyridinesbyoxidativecouplingwitharylacylperoxides |