Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS: Rg1 excretion in rat bile, urine and feces

Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS: Rg1 excretion in rat bile, urine and feces

Ginsenoside Rg1 (Rg1), the major effective component of ginseng, has been shown to have multiple bioactivities, but low oral bioavailability. The aim of this study was to develop a simple, sensitive and rapid high performance liquid chromatography–tandem mass spectrometry (LC–MS/MS) method, which co...

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Bibliographic Details
Main Authors: Chiyu He, Ru Feng, Yupeng Sun, Shifeng Chu, Ji Chen, Chao Ma, Jie Fu, Zhenxiong Zhao, Min Huang, Jiawen Shou, Xiaoyang Li, Yuzhu Wang, Jinfeng Hu, Yan Wang, Juntian Zhang
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Ginsenoside Rg1
Ginsenoside Rh1
Protopanaxatriol
Excretion
LC–MS/MS
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383516301769

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