Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley Rat
This study evaluated the lignan contents of raw omija (R) and sugared omija (S), byproducts discarded after the use of raw omija, by HPLC and determined their bioactivity by feeding rats R and S for eight weeks. S retained 63% more lignan than R. Body weight gains in the raw omija-fed group (RO) and...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-09-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/8/9/373 |
| _version_ | 1818451398990233600 |
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| author | Sung-Hyun Hwa Su-Jung Yeon Go-Eun Hong Won-Young Cho Ha-Jung Lee Ji-Han Kim Chi-Ho Lee |
| author_facet | Sung-Hyun Hwa Su-Jung Yeon Go-Eun Hong Won-Young Cho Ha-Jung Lee Ji-Han Kim Chi-Ho Lee |
| author_sort | Sung-Hyun Hwa |
| collection | DOAJ |
| description | This study evaluated the lignan contents of raw omija (R) and sugared omija (S), byproducts discarded after the use of raw omija, by HPLC and determined their bioactivity by feeding rats R and S for eight weeks. S retained 63% more lignan than R. Body weight gains in the raw omija-fed group (RO) and sugared omija-fed group (SO) decreased significantly compared to that of the control group (CON, <i>p</i> < 0.05). Glucose and aspartate aminotransferase levels in the serum of the experimental groups were lower than those in CON, especially in SO (<i>p</i> < 0.05). The amount of atrial natriuretic peptide in RO decreased significantly compared to that in CON (<i>p</i> < 0.05). The renin activity in RO increased and that in SO decreased compared to the same in CON (<i>p</i> > 0.05). Therefore, it was suggested that sugared omija contains lignan compounds and potentially contributes to bioactivity in that it decreases blood glucose levels and blood pressure. |
| first_indexed | 2024-12-14T21:06:34Z |
| format | Article |
| id | doaj.art-a62cc3ce784a4287be9364ff8d0bb4f8 |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-12-14T21:06:34Z |
| publishDate | 2019-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-a62cc3ce784a4287be9364ff8d0bb4f82022-12-21T22:47:25ZengMDPI AGFoods2304-81582019-09-018937310.3390/foods8090373foods8090373Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley RatSung-Hyun Hwa0Su-Jung Yeon1Go-Eun Hong2Won-Young Cho3Ha-Jung Lee4Ji-Han Kim5Chi-Ho Lee6Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, KoreaDepartment of Agricultural, Life and Environmental Science, Tottori University, Tottori 680-8550, JapanLab supervisor, Factory, Royal Canin Korea, Jeollabuk-do 54325, KoreaDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, KoreaDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, KoreaAgResearch (Grasslands Research Centre), Palmerston North 4442, New ZealandDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, KoreaThis study evaluated the lignan contents of raw omija (R) and sugared omija (S), byproducts discarded after the use of raw omija, by HPLC and determined their bioactivity by feeding rats R and S for eight weeks. S retained 63% more lignan than R. Body weight gains in the raw omija-fed group (RO) and sugared omija-fed group (SO) decreased significantly compared to that of the control group (CON, <i>p</i> < 0.05). Glucose and aspartate aminotransferase levels in the serum of the experimental groups were lower than those in CON, especially in SO (<i>p</i> < 0.05). The amount of atrial natriuretic peptide in RO decreased significantly compared to that in CON (<i>p</i> < 0.05). The renin activity in RO increased and that in SO decreased compared to the same in CON (<i>p</i> > 0.05). Therefore, it was suggested that sugared omija contains lignan compounds and potentially contributes to bioactivity in that it decreases blood glucose levels and blood pressure.https://www.mdpi.com/2304-8158/8/9/373omija<i>Schizandra chinensis</i>sugared omijabyproductrenin |
| spellingShingle | Sung-Hyun Hwa Su-Jung Yeon Go-Eun Hong Won-Young Cho Ha-Jung Lee Ji-Han Kim Chi-Ho Lee Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley Rat Foods omija <i>Schizandra chinensis</i> sugared omija byproduct renin |
| title | Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley Rat |
| title_full | Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley Rat |
| title_fullStr | Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley Rat |
| title_full_unstemmed | Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley Rat |
| title_short | Evaluation of Lignan Compound Content and Bioactivity of Raw Omija and Sugared Omija in Serum of Sprague Dawley Rat |
| title_sort | evaluation of lignan compound content and bioactivity of raw omija and sugared omija in serum of sprague dawley rat |
| topic | omija <i>Schizandra chinensis</i> sugared omija byproduct renin |
| url | https://www.mdpi.com/2304-8158/8/9/373 |
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