The oral-brain axis: can periodontal pathogens trigger the onset and progression of Alzheimer’s disease?

The oral-brain axis: can periodontal pathogens trigger the onset and progression of Alzheimer’s disease?

Alzheimer’s disease (AD) is the most prevalent form of dementia, characterized by a progressive cognitive decline. Sporadic AD, accounting for more than 95% of cases, may arise due to the influence of environmental factors. It was reported that periodontitis, a common oral ailment, shares several ri...

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Bibliographic Details
Main Authors: Ruohan Li, Junnan Wang, Wei Xiong, Yu Luo, Huixian Feng, Heng Zhou, Youjian Peng, Yan He, Qingsong Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Microbiology
Subjects:
Alzheimer’s disease
periodontal pathogen
neuroinflammation
periodontitis
neurodegeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1358179/full

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