Influence of the Timing of Leptomeningeal Metastasis on the Outcome of <i>EGFR</i>-Mutant Lung Adenocarcinoma Patients and Predictors of Detectable <i>EGFR</i> Mutations in Cerebrospinal Fluid

Influence of the Timing of Leptomeningeal Metastasis on the Outcome of <i>EGFR</i>-Mutant Lung Adenocarcinoma Patients and Predictors of Detectable <i>EGFR</i> Mutations in Cerebrospinal Fluid

Background: We aim to evaluate the influence of the timing of leptomeningeal metastasis (LM) occurrence on the outcome of <i>EGFR</i>-mutant lung adenocarcinoma and to explore the predictors of detectable <i>EGFR</i> mutation in the cerebrospinal fluid (CSF). Methods: <i&g...

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Main Authors: Pei-Ya Liao, Wei-Fan Ou, Kang-Yi Su, Ming-Hsi Sun, Chih-Mei Huang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Sung-Liang Yu, Yen-Hsiang Huang, Jeng-Sen Tseng, Tsung-Ying Yang, Gee-Chen Chang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
epidermal growth factor receptor (EGFR)
lung adenocarcinoma
leptomeningeal metastasis
cerebrospinal fluid (CSF)
Online Access:https://www.mdpi.com/2072-6694/14/12/2824

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