Unravelling the Role of Glycogen Synthase Kinase-3 in Alzheimer’s Disease-Related Epileptic Seizures

Unravelling the Role of Glycogen Synthase Kinase-3 in Alzheimer’s Disease-Related Epileptic Seizures

Alzheimer’s disease (AD) is the most common form of dementia. An increasing body of evidence describes an elevated incidence of epilepsy in patients with AD, and many transgenic animal models of AD also exhibit seizures and susceptibility to epilepsy. However, the biological mechanisms that underlie...

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Bibliographic Details
Main Authors: Runxuan Lin, Nigel Charles Jones, Patrick Kwan
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
Glycogen synthase kinase 3
Alzheimer’s disease
Epileptic seizures
Hyperphosphorylated tau
Amyloid beta
Online Access:https://www.mdpi.com/1422-0067/21/10/3676

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