Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic
Background: To define changes in AMI case rates, patient demographics, cardiovascular comorbidities, treatment approaches, in-hospital outcomes, and the economic burden of COVID-19 during the pandemic. Methods: We conducted a multicenter, observational survey with selected hospitals from three medic...
| Main Authors: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-12-01
|
| Series: | International Journal of Cardiology: Heart & Vasculature |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352906723001197 |
| _version_ | 1797398581492056064 |
|---|---|
| author | Hamid Pourasghari Pirhossein Kolivand Samad Azari Peyman Saberian Masoud Behzadifar Negar Omidi Shahrzad Salehbeigi Behzad Raei Soheila Rajaie Nicola Luigi Bragazzi Reza Golpira Mohammd Rafie Khorgami Mohammad Khani Sara Montazerinamin Farhad Lotfi Masih Tajdini |
| author_facet | Hamid Pourasghari Pirhossein Kolivand Samad Azari Peyman Saberian Masoud Behzadifar Negar Omidi Shahrzad Salehbeigi Behzad Raei Soheila Rajaie Nicola Luigi Bragazzi Reza Golpira Mohammd Rafie Khorgami Mohammad Khani Sara Montazerinamin Farhad Lotfi Masih Tajdini |
| author_sort | Hamid Pourasghari |
| collection | DOAJ |
| description | Background: To define changes in AMI case rates, patient demographics, cardiovascular comorbidities, treatment approaches, in-hospital outcomes, and the economic burden of COVID-19 during the pandemic. Methods: We conducted a multicenter, observational survey with selected hospitals from three medical universities in Tehran city. A data collection tool consisting of three parts. The first part included socio-demographic information, and the second part included clinical information, major complications, and in-hospital mortality. Finally, the third part was related to the direct medical costs generated by AMI in COVID-19 and non-COVID-19 patients. The study cohort comprised 4,560 hospitalizations for AMI (2,935 for STEMI [64%] and 1,625 for NSTEMI [36%]). Results: Of those hospitalized for AMI, 1,864 (76.6 %) and 1,659 (78 %) were male before the COVID-19 outbreak and during the COVID-19 era, respectively. The length of stay (LOS), was significantly lower during the COVID-19 pandemic era (4.27 ± 3.63 vs 5.24 ± 5.17, p = 0.00). Results showed that there were no significant differences in terms of patient risk factors across periods. A total of 2,126 AMIs were registered during the COVID-19 era, with a 12.65 % reduction (95 % CI 1.5–25.1) compared with the equivalent time in 2019 (P = 0.179). The risk of in-hospital mortality rate for AMI patients increased from 4.9 % in 2019 to 7.0 % in the COVID-19 era (OR = 1.42; 95 % CI 1.11–1.82; P = 0.004). Major complications were registered in 9.7 % of cases in 2020, which is higher than the rate of 6.6 % reported in 2019 (OR = 1.46, 95 % CI 1.11–1.82; P = 0.000). Total costs in hospitalized AMI-COVID patients averaged $188 more than in AMI patients (P = 0.020). Conclusion: This cross-sectional study found important changes in AMI hospitalization rates, worse outcomes, and higher costs during the COVID-19 periods. Future studies are recommended to examine the long-term outcomes of hospitalized AMI patients during the COVID-19 era. |
| first_indexed | 2024-03-09T01:27:33Z |
| format | Article |
| id | doaj.art-a63c47008ab44e6991d7e68001d1f403 |
| institution | Directory Open Access Journal |
| issn | 2352-9067 |
| language | English |
| last_indexed | 2024-03-09T01:27:33Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology: Heart & Vasculature |
| spelling | doaj.art-a63c47008ab44e6991d7e68001d1f4032023-12-10T06:16:28ZengElsevierInternational Journal of Cardiology: Heart & Vasculature2352-90672023-12-0149101288Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemicHamid Pourasghari0Pirhossein Kolivand1Samad Azari2Peyman Saberian3Masoud Behzadifar4Negar Omidi5Shahrzad Salehbeigi6Behzad Raei7Soheila Rajaie8Nicola Luigi Bragazzi9Reza Golpira10Mohammd Rafie Khorgami11Mohammad Khani12Sara Montazerinamin13Farhad Lotfi14Masih Tajdini15Hospital Management Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, IranDepartment of Health Economics, Faculty of Medicine, Shahed University, Tehran, IranHospital Management Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran; Corresponding author at: Iran University of Medical Sciences, No. 6, Rashid Yasemi Street, Valie-Asr Avenue, Tehran 1996713883, Iran.Department of Anesthesiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranSocial Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, IranTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, IranTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, IranRazi Educational and Therapeutic Center, Tabriz University of Medical Science, Tabriz, IranResearch Center for Emergency and Disaster Resilience, Red Crescent Society of the Islamic Republic of Iran, Tehran, IranHospital Management Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, IranRajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranRajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, IranNational Center for Health Insurance Research, Tehran, IranTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, IranBackground: To define changes in AMI case rates, patient demographics, cardiovascular comorbidities, treatment approaches, in-hospital outcomes, and the economic burden of COVID-19 during the pandemic. Methods: We conducted a multicenter, observational survey with selected hospitals from three medical universities in Tehran city. A data collection tool consisting of three parts. The first part included socio-demographic information, and the second part included clinical information, major complications, and in-hospital mortality. Finally, the third part was related to the direct medical costs generated by AMI in COVID-19 and non-COVID-19 patients. The study cohort comprised 4,560 hospitalizations for AMI (2,935 for STEMI [64%] and 1,625 for NSTEMI [36%]). Results: Of those hospitalized for AMI, 1,864 (76.6 %) and 1,659 (78 %) were male before the COVID-19 outbreak and during the COVID-19 era, respectively. The length of stay (LOS), was significantly lower during the COVID-19 pandemic era (4.27 ± 3.63 vs 5.24 ± 5.17, p = 0.00). Results showed that there were no significant differences in terms of patient risk factors across periods. A total of 2,126 AMIs were registered during the COVID-19 era, with a 12.65 % reduction (95 % CI 1.5–25.1) compared with the equivalent time in 2019 (P = 0.179). The risk of in-hospital mortality rate for AMI patients increased from 4.9 % in 2019 to 7.0 % in the COVID-19 era (OR = 1.42; 95 % CI 1.11–1.82; P = 0.004). Major complications were registered in 9.7 % of cases in 2020, which is higher than the rate of 6.6 % reported in 2019 (OR = 1.46, 95 % CI 1.11–1.82; P = 0.000). Total costs in hospitalized AMI-COVID patients averaged $188 more than in AMI patients (P = 0.020). Conclusion: This cross-sectional study found important changes in AMI hospitalization rates, worse outcomes, and higher costs during the COVID-19 periods. Future studies are recommended to examine the long-term outcomes of hospitalized AMI patients during the COVID-19 era.http://www.sciencedirect.com/science/article/pii/S2352906723001197COVID-19Acute myocardial infarctionCardiac care unitsEconomic burden |
| spellingShingle | Hamid Pourasghari Pirhossein Kolivand Samad Azari Peyman Saberian Masoud Behzadifar Negar Omidi Shahrzad Salehbeigi Behzad Raei Soheila Rajaie Nicola Luigi Bragazzi Reza Golpira Mohammd Rafie Khorgami Mohammad Khani Sara Montazerinamin Farhad Lotfi Masih Tajdini Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic International Journal of Cardiology: Heart & Vasculature COVID-19 Acute myocardial infarction Cardiac care units Economic burden |
| title | Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic |
| title_full | Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic |
| title_fullStr | Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic |
| title_full_unstemmed | Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic |
| title_short | Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic |
| title_sort | epidemiological clinical and economic burden of myocardial infarction patients in iran during the covid 19 pandemic |
| topic | COVID-19 Acute myocardial infarction Cardiac care units Economic burden |
| url | http://www.sciencedirect.com/science/article/pii/S2352906723001197 |
| work_keys_str_mv | AT hamidpourasghari epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT pirhosseinkolivand epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT samadazari epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT peymansaberian epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT masoudbehzadifar epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT negaromidi epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT shahrzadsalehbeigi epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT behzadraei epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT soheilarajaie epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT nicolaluigibragazzi epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT rezagolpira epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT mohammdrafiekhorgami epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT mohammadkhani epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT saramontazerinamin epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT farhadlotfi epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic AT masihtajdini epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic |