Effects of mechanical stimulation on the reprogramming of somatic cells into human-induced pluripotent stem cells

Effects of mechanical stimulation on the reprogramming of somatic cells into human-induced pluripotent stem cells

Abstract Background Mechanical stimuli play important roles in the proliferation and differentiation of adult stem cells. However, few studies on their effects on induced pluripotent stem cells (iPSCs) have been published. Methods Human dermal fibroblasts were seeded onto flexible membrane-bottom pl...

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Bibliographic Details
Main Authors: Young Mi Kim, Yun Gyeong Kang, So Hee Park, Myung-Kwan Han, Jae Ho Kim, Ji Won Shin, Jung-Woog Shin
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Stem Cell Research & Therapy
Subjects:
Human-induced pluripotent stem cells
Cell reprogramming
Reprogramming factors
Human dermal fibroblasts
Mechanical stimulation
Equiaxial stretching
Online Access:http://link.springer.com/article/10.1186/s13287-017-0594-2

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