Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine

The metabolic balances of sulfur in two cases of hepatolenticular degeneration were studied. A positive balance was found in both cases; in one patient submitted to mixed diet, the average was significantly higher than the normal mean. The administration of D-penicillamine promoted a marked increase...

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Main Authors: Horacio M. Canelas, Francisco B. De Jorge, Waldir A. Tognola
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 1969-12-01
Series:Arquivos de Neuro-Psiquiatria
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1969000400003&lng=en&tlng=en
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author Horacio M. Canelas
Francisco B. De Jorge
Waldir A. Tognola
author_facet Horacio M. Canelas
Francisco B. De Jorge
Waldir A. Tognola
author_sort Horacio M. Canelas
collection DOAJ
description The metabolic balances of sulfur in two cases of hepatolenticular degeneration were studied. A positive balance was found in both cases; in one patient submitted to mixed diet, the average was significantly higher than the normal mean. The administration of D-penicillamine promoted a marked increase in the urinary excretion of sulfur, leading to a strongly negative balance. The blood sulfur contents, which were normal in the control periods, showed a progressive increment after D-penicillamine was started.
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spelling doaj.art-a640e5576d0e411a899c0ceacab6ba112022-12-21T22:49:35ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42271969-12-0127426627010.1590/S0004-282X1969000400003S0004-282X1969000400003Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamineHoracio M. Canelas0Francisco B. De Jorge1Waldir A. Tognola2Universidade de São PauloUniversidade de São PauloUniversidade de São PauloThe metabolic balances of sulfur in two cases of hepatolenticular degeneration were studied. A positive balance was found in both cases; in one patient submitted to mixed diet, the average was significantly higher than the normal mean. The administration of D-penicillamine promoted a marked increase in the urinary excretion of sulfur, leading to a strongly negative balance. The blood sulfur contents, which were normal in the control periods, showed a progressive increment after D-penicillamine was started.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1969000400003&lng=en&tlng=en
spellingShingle Horacio M. Canelas
Francisco B. De Jorge
Waldir A. Tognola
Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine
Arquivos de Neuro-Psiquiatria
title Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine
title_full Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine
title_fullStr Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine
title_full_unstemmed Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine
title_short Metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of D-penicillamine
title_sort metabolic balances of sulfur in patients with hepatolenticular degeneration and effect of the use of d penicillamine
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1969000400003&lng=en&tlng=en
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AT franciscobdejorge metabolicbalancesofsulfurinpatientswithhepatolenticulardegenerationandeffectoftheuseofdpenicillamine
AT waldiratognola metabolicbalancesofsulfurinpatientswithhepatolenticulardegenerationandeffectoftheuseofdpenicillamine