Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects
Abstract Nauclea officinalis (N. officinalis), a medicinal plant of the genus Nauclea in the family Rubiaceae, is used in the treatment of fever, pneumonia, pharyngolaryngitis, and enteritis in China. Extracts of N. officinalis include alkaloids, phenolic acids, pentacyclic triterpenoids, and flavon...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-12-01
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| Series: | Chinese Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13020-022-00691-8 |
| _version_ | 1797977285207261184 |
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| author | Bin Liu Qi Geng Zhiwen Cao Li Li Peipei Lu Lin Lin Lan Yan Cheng Lu |
| author_facet | Bin Liu Qi Geng Zhiwen Cao Li Li Peipei Lu Lin Lin Lan Yan Cheng Lu |
| author_sort | Bin Liu |
| collection | DOAJ |
| description | Abstract Nauclea officinalis (N. officinalis), a medicinal plant of the genus Nauclea in the family Rubiaceae, is used in the treatment of fever, pneumonia, pharyngolaryngitis, and enteritis in China. Extracts of N. officinalis include alkaloids, phenolic acids, pentacyclic triterpenoids, and flavonoids, which exert all kinds of pharmacological effects, for instance anti-inflammatory, anti-tumor, antibacterial, and antiviral and therefore show good effectiveness. To gain a comprehensive and deep understanding, the medicinal chemistry and chemical biology of N. officinalis are summarized in this review to provide a theoretical basis. The pharmacological effects were reviewed to provide evidence or insights into potential opportunities for further studies and medicinal exploitation of N. officinalis. |
| first_indexed | 2024-04-11T05:04:26Z |
| format | Article |
| id | doaj.art-a643a2591c444c8a81812347053f60d4 |
| institution | Directory Open Access Journal |
| issn | 1749-8546 |
| language | English |
| last_indexed | 2024-04-11T05:04:26Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Chinese Medicine |
| spelling | doaj.art-a643a2591c444c8a81812347053f60d42022-12-25T12:29:24ZengBMCChinese Medicine1749-85462022-12-0117112510.1186/s13020-022-00691-8Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effectsBin Liu0Qi Geng1Zhiwen Cao2Li Li3Peipei Lu4Lin Lin5Lan Yan6Cheng Lu7Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical SciencesAbstract Nauclea officinalis (N. officinalis), a medicinal plant of the genus Nauclea in the family Rubiaceae, is used in the treatment of fever, pneumonia, pharyngolaryngitis, and enteritis in China. Extracts of N. officinalis include alkaloids, phenolic acids, pentacyclic triterpenoids, and flavonoids, which exert all kinds of pharmacological effects, for instance anti-inflammatory, anti-tumor, antibacterial, and antiviral and therefore show good effectiveness. To gain a comprehensive and deep understanding, the medicinal chemistry and chemical biology of N. officinalis are summarized in this review to provide a theoretical basis. The pharmacological effects were reviewed to provide evidence or insights into potential opportunities for further studies and medicinal exploitation of N. officinalis.https://doi.org/10.1186/s13020-022-00691-8Nauclea officinalisPhytochemistryBiological activityPharmacological effect |
| spellingShingle | Bin Liu Qi Geng Zhiwen Cao Li Li Peipei Lu Lin Lin Lan Yan Cheng Lu Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects Chinese Medicine Nauclea officinalis Phytochemistry Biological activity Pharmacological effect |
| title | Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects |
| title_full | Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects |
| title_fullStr | Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects |
| title_full_unstemmed | Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects |
| title_short | Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects |
| title_sort | nauclea officinalis a chinese medicinal herb with phytochemical biological and pharmacological effects |
| topic | Nauclea officinalis Phytochemistry Biological activity Pharmacological effect |
| url | https://doi.org/10.1186/s13020-022-00691-8 |
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