The Role of Non-Structural Protein NSs in the Pathogenesis of Severe Fever with Thrombocytopenia Syndrome

The Role of Non-Structural Protein NSs in the Pathogenesis of Severe Fever with Thrombocytopenia Syndrome

Viral non-structural proteins, such as NSs of the newly emerging severe fever with thrombocytopenia syndrome virus, are well established virulence factors, mediating viral pathogenesis and disease progression through various mechanisms. NSs has been described as a potent interferon antagonist and NF...

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Bibliographic Details
Main Authors: Jumana Khalil, Hiroki Kato, Takashi Fujita
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
SFTSV NSs
NF-κB
cytokine storm
TBK1
viral pathogenesis
interferons
Online Access:https://www.mdpi.com/1999-4915/13/5/876

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