A clinicopathological study of facial granulomatous dermatoses: A hospital-based study
Background: Granulomatous dermatoses of various types, etiologies, and clinical features frequently present with similar clinicopathological features which create a dilemma and diagnostic challenge for experts. Early diagnosis of facial lesions is of prime concern due to potential social stigma and...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Indian Journal of Dermatopathology and Diagnostic Dermatology |
| Subjects: | |
| Online Access: | http://www.ijdpdd.com/article.asp?issn=2349-6029;year=2019;volume=6;issue=1;spage=25;epage=29;aulast=Mathur |
| _version_ | 1818129059180183552 |
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| author | Mahesh Mathur Alina Karki Prakash Acharya Ayush Jha |
| author_facet | Mahesh Mathur Alina Karki Prakash Acharya Ayush Jha |
| author_sort | Mahesh Mathur |
| collection | DOAJ |
| description | Background: Granulomatous dermatoses of various types, etiologies, and clinical features frequently present with similar clinicopathological features which create a dilemma and diagnostic challenge for experts. Early diagnosis of facial lesions is of prime concern due to potential social stigma and psychological stress because of cosmetic disfigurement. Objective: To study the epidemiological and clinicopathological features of various granulomatous facial skin lesions and their concordance rate. Materials and Methods: A retrospective, hospital-based study was carried out at the Department of Dermatology, College of Medical Sciences, Bharatpur, over a period of 5 years (January 2013–January 2018). All clinically suspected cases of facial granulomatous dermatoses were included, their clinical and histological findings were recorded and analyzed according to the standard protocol, and a clinicopathological correlation was ascertained. Results: Among 850 skin biopsies performed during the study, 30 cases were clinically suspected as facial granulomatous dermatoses. There was female predominance (n = 22, 73.33%), and the mean age of patients was 41.7 years. Majority of cases (n = 29, 96.66%) were of infectious origin with leprosy as predominant cause (n = 25, 83.33%), followed by cutaneous tuberculosis (n = 4, 13.33%). Histologically, epithelioid cell granulomas (n = 26, 86.67%) and histiocytic granuloma (n = 3, 10%) were observed. Fite Faraco stain was positive in 6 (20%) cases of leprosy. An overall concordance rate of 80% was observed in facial granulomatous dermatoses in our study. Conclusion: In our study, infectious etiology is the most common cause of facial granulomatous dermatoses. Among infections, leprosy is the most common. |
| first_indexed | 2024-12-11T07:43:07Z |
| format | Article |
| id | doaj.art-a644cafff97b4e268f2eb53e3cc39a55 |
| institution | Directory Open Access Journal |
| issn | 2349-6029 2349-6029 |
| language | English |
| last_indexed | 2024-12-11T07:43:07Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatopathology and Diagnostic Dermatology |
| spelling | doaj.art-a644cafff97b4e268f2eb53e3cc39a552022-12-22T01:15:31ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatopathology and Diagnostic Dermatology2349-60292349-60292019-01-0161252910.4103/ijdpdd.ijdpdd_51_18A clinicopathological study of facial granulomatous dermatoses: A hospital-based studyMahesh MathurAlina KarkiPrakash AcharyaAyush JhaBackground: Granulomatous dermatoses of various types, etiologies, and clinical features frequently present with similar clinicopathological features which create a dilemma and diagnostic challenge for experts. Early diagnosis of facial lesions is of prime concern due to potential social stigma and psychological stress because of cosmetic disfigurement. Objective: To study the epidemiological and clinicopathological features of various granulomatous facial skin lesions and their concordance rate. Materials and Methods: A retrospective, hospital-based study was carried out at the Department of Dermatology, College of Medical Sciences, Bharatpur, over a period of 5 years (January 2013–January 2018). All clinically suspected cases of facial granulomatous dermatoses were included, their clinical and histological findings were recorded and analyzed according to the standard protocol, and a clinicopathological correlation was ascertained. Results: Among 850 skin biopsies performed during the study, 30 cases were clinically suspected as facial granulomatous dermatoses. There was female predominance (n = 22, 73.33%), and the mean age of patients was 41.7 years. Majority of cases (n = 29, 96.66%) were of infectious origin with leprosy as predominant cause (n = 25, 83.33%), followed by cutaneous tuberculosis (n = 4, 13.33%). Histologically, epithelioid cell granulomas (n = 26, 86.67%) and histiocytic granuloma (n = 3, 10%) were observed. Fite Faraco stain was positive in 6 (20%) cases of leprosy. An overall concordance rate of 80% was observed in facial granulomatous dermatoses in our study. Conclusion: In our study, infectious etiology is the most common cause of facial granulomatous dermatoses. Among infections, leprosy is the most common.http://www.ijdpdd.com/article.asp?issn=2349-6029;year=2019;volume=6;issue=1;spage=25;epage=29;aulast=MathurFacegranulomagranulomatous dermatosesleprosylupus vulgaris |
| spellingShingle | Mahesh Mathur Alina Karki Prakash Acharya Ayush Jha A clinicopathological study of facial granulomatous dermatoses: A hospital-based study Indian Journal of Dermatopathology and Diagnostic Dermatology Face granuloma granulomatous dermatoses leprosy lupus vulgaris |
| title | A clinicopathological study of facial granulomatous dermatoses: A hospital-based study |
| title_full | A clinicopathological study of facial granulomatous dermatoses: A hospital-based study |
| title_fullStr | A clinicopathological study of facial granulomatous dermatoses: A hospital-based study |
| title_full_unstemmed | A clinicopathological study of facial granulomatous dermatoses: A hospital-based study |
| title_short | A clinicopathological study of facial granulomatous dermatoses: A hospital-based study |
| title_sort | clinicopathological study of facial granulomatous dermatoses a hospital based study |
| topic | Face granuloma granulomatous dermatoses leprosy lupus vulgaris |
| url | http://www.ijdpdd.com/article.asp?issn=2349-6029;year=2019;volume=6;issue=1;spage=25;epage=29;aulast=Mathur |
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