Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Abstract Background In multiple sclerosis, coagulation factors have been shown to modulate inflammation. In this translational study, we investigated whether long-term anticoagulation with warfarin or rivaroxaban has beneficial effects on the course of autoimmune experimental encephalomyelitis (EAE)...

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Detalles Bibliográficos
Autores principales: Leonie Stolz, Amin Derouiche, Kavi Devraj, Frank Weber, Robert Brunkhorst, Christian Foerch
Formato: Artículo
Lenguaje:English
Publicado: BMC 2017-07-01
Colección:Journal of Neuroinflammation
Materias:
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Inflammation
Mice
Anticoagulation
Acceso en línea:http://link.springer.com/article/10.1186/s12974-017-0926-2

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