Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Abstract Background In multiple sclerosis, coagulation factors have been shown to modulate inflammation. In this translational study, we investigated whether long-term anticoagulation with warfarin or rivaroxaban has beneficial effects on the course of autoimmune experimental encephalomyelitis (EAE)...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Leonie Stolz, Amin Derouiche, Kavi Devraj, Frank Weber, Robert Brunkhorst, Christian Foerch
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2017-07-01
Schriftenreihe:Journal of Neuroinflammation
Schlagworte:
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Inflammation
Mice
Anticoagulation
Online Zugang:http://link.springer.com/article/10.1186/s12974-017-0926-2

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