Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Abstract Background In multiple sclerosis, coagulation factors have been shown to modulate inflammation. In this translational study, we investigated whether long-term anticoagulation with warfarin or rivaroxaban has beneficial effects on the course of autoimmune experimental encephalomyelitis (EAE)...

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Bibliographic Details
Main Authors: Leonie Stolz, Amin Derouiche, Kavi Devraj, Frank Weber, Robert Brunkhorst, Christian Foerch
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Inflammation
Mice
Anticoagulation
Online Access:http://link.springer.com/article/10.1186/s12974-017-0926-2

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