Late onset Leigh syndrome: about an observation
Leigh Syndrome (LS) is a rare childhood mitochondriopathy characterized by clinical polymorphism. Generally, it begins at the age of 2 years .We report the case of a 13 year old patient, born from on inbred marriage,she resented a significant decrease of visual acuity at the age of 9 years. Toward...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Oran 1
2020-12-01
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| Series: | Journal de la Faculté de Médecine d'Oran |
| Subjects: | |
| Online Access: | https://www.ajol.info/index.php/jfmo/article/view/226768 |
| Summary: | Leigh Syndrome (LS) is a rare childhood mitochondriopathy characterized by clinical polymorphism. Generally, it begins at the age of 2 years .We report the case of a 13 year old patient, born from on inbred marriage,she resented a significant decrease of visual acuity at the age of 9 years.
Towards the age of 13 years, she presented bulbar and walking disorders. The neurological examination found a ppyramidal, an extrapyramidal,
a neurogenic syndromes and a kyphoscoliosis. Brain MRI objectified a bilateral and symmetrical hyper signal in the brainstem, the basal ganglia and the periaqueductal region. Brain spectro-MRI found a peak in lactates.
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| ISSN: | 2571-9874 2602-6511 |