Late onset Leigh syndrome: about an observation
Leigh Syndrome (LS) is a rare childhood mitochondriopathy characterized by clinical polymorphism. Generally, it begins at the age of 2 years .We report the case of a 13 year old patient, born from on inbred marriage,she resented a significant decrease of visual acuity at the age of 9 years. Toward...
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| Format: | Article |
| Language: | English |
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University of Oran 1
2020-12-01
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| Series: | Journal de la Faculté de Médecine d'Oran |
| Subjects: | |
| Online Access: | https://www.ajol.info/index.php/jfmo/article/view/226768 |
| _version_ | 1828717075459211264 |
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| author | ahira BARKA-BEDRANE Djaoued BOUCHENAK-KHELLADI Cherifa LOUHIBI Hakim CHIALI |
| author_facet | ahira BARKA-BEDRANE Djaoued BOUCHENAK-KHELLADI Cherifa LOUHIBI Hakim CHIALI |
| author_sort | ahira BARKA-BEDRANE |
| collection | DOAJ |
| description |
Leigh Syndrome (LS) is a rare childhood mitochondriopathy characterized by clinical polymorphism. Generally, it begins at the age of 2 years .We report the case of a 13 year old patient, born from on inbred marriage,she resented a significant decrease of visual acuity at the age of 9 years.
Towards the age of 13 years, she presented bulbar and walking disorders. The neurological examination found a ppyramidal, an extrapyramidal,
a neurogenic syndromes and a kyphoscoliosis. Brain MRI objectified a bilateral and symmetrical hyper signal in the brainstem, the basal ganglia and the periaqueductal region. Brain spectro-MRI found a peak in lactates.
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| first_indexed | 2024-03-12T14:22:38Z |
| format | Article |
| id | doaj.art-a64a3a96fe494df9bf56ecf68d7b56ab |
| institution | Directory Open Access Journal |
| issn | 2571-9874 2602-6511 |
| language | English |
| last_indexed | 2024-03-12T14:22:38Z |
| publishDate | 2020-12-01 |
| publisher | University of Oran 1 |
| record_format | Article |
| series | Journal de la Faculté de Médecine d'Oran |
| spelling | doaj.art-a64a3a96fe494df9bf56ecf68d7b56ab2023-08-18T19:41:54ZengUniversity of Oran 1Journal de la Faculté de Médecine d'Oran2571-98742602-65112020-12-0142Late onset Leigh syndrome: about an observation ahira BARKA-BEDRANE0Djaoued BOUCHENAK-KHELLADI1Cherifa LOUHIBI2Hakim CHIALI3Service de neurologie Centre hospitalo universitaire Dr Tidjani Damerdji Tlemcen Faculté de médecine, université Abou Bekr Belkaid TlemcenService de neurologie Centre hospitalo universitaire Dr Tidjani Damerdji Tlemcen Faculté de médecine, université Abou Bekr Belkaid TlemcenService de neurologie Centre hospitalo universitaire Dr Tidjani Damerdji TlemcenFaculté de médecine, université Abou Bekr Belkaid TlemcenService de neurologie Centre hospitalo universitaire Dr Tidjani Damerdji Tlemcen Faculté de médecine, université Abou Bekr Belkaid Tlemcen Leigh Syndrome (LS) is a rare childhood mitochondriopathy characterized by clinical polymorphism. Generally, it begins at the age of 2 years .We report the case of a 13 year old patient, born from on inbred marriage,she resented a significant decrease of visual acuity at the age of 9 years. Towards the age of 13 years, she presented bulbar and walking disorders. The neurological examination found a ppyramidal, an extrapyramidal, a neurogenic syndromes and a kyphoscoliosis. Brain MRI objectified a bilateral and symmetrical hyper signal in the brainstem, the basal ganglia and the periaqueductal region. Brain spectro-MRI found a peak in lactates. https://www.ajol.info/index.php/jfmo/article/view/226768Leigh syndromelate onsetrare mitochondrial disorder |
| spellingShingle | ahira BARKA-BEDRANE Djaoued BOUCHENAK-KHELLADI Cherifa LOUHIBI Hakim CHIALI Late onset Leigh syndrome: about an observation Journal de la Faculté de Médecine d'Oran Leigh syndrome late onset rare mitochondrial disorder |
| title | Late onset Leigh syndrome: about an observation |
| title_full | Late onset Leigh syndrome: about an observation |
| title_fullStr | Late onset Leigh syndrome: about an observation |
| title_full_unstemmed | Late onset Leigh syndrome: about an observation |
| title_short | Late onset Leigh syndrome: about an observation |
| title_sort | late onset leigh syndrome about an observation |
| topic | Leigh syndrome late onset rare mitochondrial disorder |
| url | https://www.ajol.info/index.php/jfmo/article/view/226768 |
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