Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report
Rationale: Leprosy, a chronic granulomatous disease often present clinically as erythema nodosum leprosum, a type 2 reaction. The involvement of cochlear part of audiovestibular system is a rarity. Patient concerns: A 26-year-old male patient with lepromatous leprosy developed bilateral sensorineura...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Asian Pacific Journal of Tropical Medicine |
| Subjects: | |
| Online Access: | http://www.apjtm.org/article.asp?issn=1995-7645;year=2023;volume=16;issue=9;spage=425;epage=427;aulast=Pawar |
| _version_ | 1797649586316115968 |
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| author | Harpreet Singh Pawar Itu Singh Harish Kumar Sagar |
| author_facet | Harpreet Singh Pawar Itu Singh Harish Kumar Sagar |
| author_sort | Harpreet Singh Pawar |
| collection | DOAJ |
| description | Rationale: Leprosy, a chronic granulomatous disease often present clinically as erythema nodosum leprosum, a type 2 reaction. The involvement of cochlear part of audiovestibular system is a rarity.
Patient concerns: A 26-year-old male patient with lepromatous leprosy developed bilateral sensorineural hearing loss (SNHL) during type 2 reactional episode.
Diagnosis: Recurrent erythema nodosum leprosum in rifampicin-resistant lepromatous leprosy.
Interventions: Corticosteroids and second-line multidrug therapy.
Outcomes: The patient improved significantly and was further referred for management of psychosocial impact due to sensorineural hearing loss.
Lessons: The hearing impairment is a rare complication of type 2 reaction. Any patient with suspected cranial nerve involvement should essentially be screened by tuning fork tests for early detection of hearing impairment and offer timely intervention as required. All high bacteriological index cases should be investigated for antimicrobial resistance in high endemic areas. |
| first_indexed | 2024-03-11T15:48:15Z |
| format | Article |
| id | doaj.art-a64ca79cc18547b087aee616f6a1ec13 |
| institution | Directory Open Access Journal |
| issn | 2352-4146 |
| language | English |
| last_indexed | 2024-03-11T15:48:15Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Pacific Journal of Tropical Medicine |
| spelling | doaj.art-a64ca79cc18547b087aee616f6a1ec132023-10-26T05:42:26ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Medicine2352-41462023-01-0116942542710.4103/1995-7645.386077Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case reportHarpreet Singh PawarItu SinghHarish Kumar SagarRationale: Leprosy, a chronic granulomatous disease often present clinically as erythema nodosum leprosum, a type 2 reaction. The involvement of cochlear part of audiovestibular system is a rarity. Patient concerns: A 26-year-old male patient with lepromatous leprosy developed bilateral sensorineural hearing loss (SNHL) during type 2 reactional episode. Diagnosis: Recurrent erythema nodosum leprosum in rifampicin-resistant lepromatous leprosy. Interventions: Corticosteroids and second-line multidrug therapy. Outcomes: The patient improved significantly and was further referred for management of psychosocial impact due to sensorineural hearing loss. Lessons: The hearing impairment is a rare complication of type 2 reaction. Any patient with suspected cranial nerve involvement should essentially be screened by tuning fork tests for early detection of hearing impairment and offer timely intervention as required. All high bacteriological index cases should be investigated for antimicrobial resistance in high endemic areas.http://www.apjtm.org/article.asp?issn=1995-7645;year=2023;volume=16;issue=9;spage=425;epage=427;aulast=Pawarleprosy reactions; erythema nodosum leprosum; sensorineural hearing loss; drug resistant leprosy |
| spellingShingle | Harpreet Singh Pawar Itu Singh Harish Kumar Sagar Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report Asian Pacific Journal of Tropical Medicine leprosy reactions; erythema nodosum leprosum; sensorineural hearing loss; drug resistant leprosy |
| title | Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report |
| title_full | Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report |
| title_fullStr | Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report |
| title_full_unstemmed | Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report |
| title_short | Type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient: A case report |
| title_sort | type 2 reaction associated sensorineural hearing loss in a drug resistant lepromatous leprosy patient a case report |
| topic | leprosy reactions; erythema nodosum leprosum; sensorineural hearing loss; drug resistant leprosy |
| url | http://www.apjtm.org/article.asp?issn=1995-7645;year=2023;volume=16;issue=9;spage=425;epage=427;aulast=Pawar |
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