Generation of Adrenal Chromaffin-like Cells from Human Pluripotent Stem Cells

Summary: Adrenomedullary chromaffin cells are catecholamine (CA)-producing cells originating from trunk neural crest (NC) via sympathoadrenal progenitors (SAPs). We generated NC and SAPs from human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) in vitro via BMP2/FGF2 exposure...

Full description

Bibliographic Details
Main Authors: Kwaku Dad Abu-Bonsrah, Dongcheng Zhang, Andrew R. Bjorksten, Mirella Dottori, Donald F. Newgreen
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Stem Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117304897