Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis
Assessing the psychological effects on children and adolescents of suffering atopic dermatitis (AD) is essential, when planning successful management. This study aimed to systematically review the literature regarding risk of mental disorders in children and adolescents with, or without, AD; and to...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-08-01
|
| Series: | Frontiers in Psychology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fpsyg.2019.01773/full |
| _version_ | 1818446652047884288 |
|---|---|
| author | Qian-Wen Xie Xiaolu Dai Xinfeng Tang Celia H. Y. Chan Cecilia L. W. Chan |
| author_facet | Qian-Wen Xie Xiaolu Dai Xinfeng Tang Celia H. Y. Chan Cecilia L. W. Chan |
| author_sort | Qian-Wen Xie |
| collection | DOAJ |
| description | Assessing the psychological effects on children and adolescents of suffering atopic dermatitis (AD) is essential, when planning successful management. This study aimed to systematically review the literature regarding risk of mental disorders in children and adolescents with, or without, AD; and to explore confounders. We identified potentially relevant studies from EMBASE, MEDLINE, PsycINFO, ERIC, the British Nursing Index, the Family and Society Studies Worldwide, the Social Work Abstracts, and the Sociological Abstracts from inception to Sep 30, 2018. Investigators independently screened titles and abstracts, and then full-texts. Investigators independently extracted data from included studies. Meta-analyses using random-effects models were performed, reporting odds ratios (ORs; 95% CIs). Thirty-seven studies (n = 2,068,911 children/ adolescents) were included. Meta-analysis of 35 studies found that children and adolescents with AD had significantly higher risk of total mental disorders than those without AD (OR = 1.652; 95% CI, 1.463–1.864). There was no significant difference in risks for ADHD (OR = 1.563; 95% CI, 1.382–1.769); sleep disorders (OR = 2.100; 95% CI, 1.322–3.336); anxiety (OR = 1.339; 95% CI, 1.062–1.687); depression (OR = 1.402 95% CI, 1.256–1.565); conduct disorder (OR = 1.494 95% CI, 1.230–1.815); or ASD (OR = 2.574; 95% CI, 1.469–4.510; Qb = 8.344, p = 0.138). Race/ethnicity of child, target of comparison, type of studies, representativeness of the sample, measures of AD and mental disorders were significant moderators for total mental disorders. Integrated, holistic, multidisciplinary management of pediatric AD is significantly important, which emphasizes the well-being of the whole person. |
| first_indexed | 2024-12-14T19:51:07Z |
| format | Article |
| id | doaj.art-a6529e9c950048fda58e1e9caeac5b52 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-12-14T19:51:07Z |
| publishDate | 2019-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-a6529e9c950048fda58e1e9caeac5b522022-12-21T22:49:24ZengFrontiers Media S.A.Frontiers in Psychology1664-10782019-08-011010.3389/fpsyg.2019.01773468328Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-AnalysisQian-Wen Xie0Xiaolu Dai1Xinfeng Tang2Celia H. Y. Chan3Cecilia L. W. Chan4Department of Social Work and Social Administration, The University of Hong Kong, Pokfulam, Hong KongDepartment of Social Work and Social Administration, Changsha Social Work College, Changsha, ChinaDepartment of Social Work and Social Administration, The University of Hong Kong, Pokfulam, Hong KongDepartment of Social Work and Social Administration, The University of Hong Kong, Pokfulam, Hong KongDepartment of Social Work and Social Administration, The University of Hong Kong, Pokfulam, Hong KongAssessing the psychological effects on children and adolescents of suffering atopic dermatitis (AD) is essential, when planning successful management. This study aimed to systematically review the literature regarding risk of mental disorders in children and adolescents with, or without, AD; and to explore confounders. We identified potentially relevant studies from EMBASE, MEDLINE, PsycINFO, ERIC, the British Nursing Index, the Family and Society Studies Worldwide, the Social Work Abstracts, and the Sociological Abstracts from inception to Sep 30, 2018. Investigators independently screened titles and abstracts, and then full-texts. Investigators independently extracted data from included studies. Meta-analyses using random-effects models were performed, reporting odds ratios (ORs; 95% CIs). Thirty-seven studies (n = 2,068,911 children/ adolescents) were included. Meta-analysis of 35 studies found that children and adolescents with AD had significantly higher risk of total mental disorders than those without AD (OR = 1.652; 95% CI, 1.463–1.864). There was no significant difference in risks for ADHD (OR = 1.563; 95% CI, 1.382–1.769); sleep disorders (OR = 2.100; 95% CI, 1.322–3.336); anxiety (OR = 1.339; 95% CI, 1.062–1.687); depression (OR = 1.402 95% CI, 1.256–1.565); conduct disorder (OR = 1.494 95% CI, 1.230–1.815); or ASD (OR = 2.574; 95% CI, 1.469–4.510; Qb = 8.344, p = 0.138). Race/ethnicity of child, target of comparison, type of studies, representativeness of the sample, measures of AD and mental disorders were significant moderators for total mental disorders. Integrated, holistic, multidisciplinary management of pediatric AD is significantly important, which emphasizes the well-being of the whole person.https://www.frontiersin.org/article/10.3389/fpsyg.2019.01773/fullpediatric atopic dermatitischildren and adolescentsmental disorderseczemaintegrative medicine |
| spellingShingle | Qian-Wen Xie Xiaolu Dai Xinfeng Tang Celia H. Y. Chan Cecilia L. W. Chan Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis Frontiers in Psychology pediatric atopic dermatitis children and adolescents mental disorders eczema integrative medicine |
| title | Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis |
| title_full | Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis |
| title_fullStr | Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis |
| title_short | Risk of Mental Disorders in Children and Adolescents With Atopic Dermatitis: A Systematic Review and Meta-Analysis |
| title_sort | risk of mental disorders in children and adolescents with atopic dermatitis a systematic review and meta analysis |
| topic | pediatric atopic dermatitis children and adolescents mental disorders eczema integrative medicine |
| url | https://www.frontiersin.org/article/10.3389/fpsyg.2019.01773/full |
| work_keys_str_mv | AT qianwenxie riskofmentaldisordersinchildrenandadolescentswithatopicdermatitisasystematicreviewandmetaanalysis AT xiaoludai riskofmentaldisordersinchildrenandadolescentswithatopicdermatitisasystematicreviewandmetaanalysis AT xinfengtang riskofmentaldisordersinchildrenandadolescentswithatopicdermatitisasystematicreviewandmetaanalysis AT celiahychan riskofmentaldisordersinchildrenandadolescentswithatopicdermatitisasystematicreviewandmetaanalysis AT cecilialwchan riskofmentaldisordersinchildrenandadolescentswithatopicdermatitisasystematicreviewandmetaanalysis |