Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients

In this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction–diffusion dynamics and mass conservation law and is considered with a delay in the cell proli...

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Bibliographic Details
Main Authors: Shihe Xu, Meng Bai, Fangwei Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Biological Dynamics
Subjects:
Online Access:http://dx.doi.org/10.1080/17513758.2017.1386804
Description
Summary:In this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction–diffusion dynamics and mass conservation law and is considered with a delay in the cell proliferation process. Using a fixed-point theorem in cones, the existence and uniqueness of almost periodic solutions for different parameter values of the model is proved. Moreover, by the Gronwall inequality, sufficient conditions are established for the exponential stability of the unique almost periodic solution. Results are illustrated by computer simulations.
ISSN:1751-3758
1751-3766