Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
In this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction–diffusion dynamics and mass conservation law and is considered with a delay in the cell proli...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-01-01
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Series: | Journal of Biological Dynamics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/17513758.2017.1386804 |
Summary: | In this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction–diffusion dynamics and mass conservation law and is considered with a delay in the cell proliferation process. Using a fixed-point theorem in cones, the existence and uniqueness of almost periodic solutions for different parameter values of the model is proved. Moreover, by the Gronwall inequality, sufficient conditions are established for the exponential stability of the unique almost periodic solution. Results are illustrated by computer simulations. |
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ISSN: | 1751-3758 1751-3766 |