Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients

In this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction–diffusion dynamics and mass conservation law and is considered with a delay in the cell proli...

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Main Authors: Shihe Xu, Meng Bai, Fangwei Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Biological Dynamics
Subjects:
Online Access:http://dx.doi.org/10.1080/17513758.2017.1386804
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author Shihe Xu
Meng Bai
Fangwei Zhang
author_facet Shihe Xu
Meng Bai
Fangwei Zhang
author_sort Shihe Xu
collection DOAJ
description In this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction–diffusion dynamics and mass conservation law and is considered with a delay in the cell proliferation process. Using a fixed-point theorem in cones, the existence and uniqueness of almost periodic solutions for different parameter values of the model is proved. Moreover, by the Gronwall inequality, sufficient conditions are established for the exponential stability of the unique almost periodic solution. Results are illustrated by computer simulations.
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spelling doaj.art-a655e27bca274c2f862e2462ea503ef32022-12-22T02:39:59ZengTaylor & Francis GroupJournal of Biological Dynamics1751-37581751-37662017-01-0111150452010.1080/17513758.2017.13868041386804Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrientsShihe Xu0Meng Bai1Fangwei Zhang2School of Mathematics and Statistics, Zhaoqing UniversitySchool of Mathematics and Statistics, Zhaoqing UniversityCollege of Transport and Communications, Shanghai Maritime UniversityIn this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction–diffusion dynamics and mass conservation law and is considered with a delay in the cell proliferation process. Using a fixed-point theorem in cones, the existence and uniqueness of almost periodic solutions for different parameter values of the model is proved. Moreover, by the Gronwall inequality, sufficient conditions are established for the exponential stability of the unique almost periodic solution. Results are illustrated by computer simulations.http://dx.doi.org/10.1080/17513758.2017.1386804Tumour growthalmost periodic solutionexistence and uniquenessexponential stability
spellingShingle Shihe Xu
Meng Bai
Fangwei Zhang
Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
Journal of Biological Dynamics
Tumour growth
almost periodic solution
existence and uniqueness
exponential stability
title Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
title_full Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
title_fullStr Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
title_full_unstemmed Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
title_short Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
title_sort analysis of a time delayed mathematical model for tumour growth with an almost periodic supply of external nutrients
topic Tumour growth
almost periodic solution
existence and uniqueness
exponential stability
url http://dx.doi.org/10.1080/17513758.2017.1386804
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