Schmidt's syndrome in a dog: a case report
This report describes a clinical case and development of the polyglandular failure syndrome including hypothyroidism and hypoadrenocorticism in a 6-year-old female Black Russian Terrier. The bitch was presented because of hypothyroidism on the first occasion. Oral supplementation with sodium levothy...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Czech Academy of Agricultural Sciences
2007-09-01
|
| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-200709-0006_schmidt-s-syndrome-in-a-dog-a-case-report.php |
| _version_ | 1797897743646064640 |
|---|---|
| author | J. Pikula J. Pikulova H. Bandouchova P. Hajkova M. Faldyna |
| author_facet | J. Pikula J. Pikulova H. Bandouchova P. Hajkova M. Faldyna |
| author_sort | J. Pikula |
| collection | DOAJ |
| description | This report describes a clinical case and development of the polyglandular failure syndrome including hypothyroidism and hypoadrenocorticism in a 6-year-old female Black Russian Terrier. The bitch was presented because of hypothyroidism on the first occasion. Oral supplementation with sodium levothyroxine resulted in clinical improvement. Four months later, it was presented again with similar and rather vague clinical signs and diagnosed with adrenocortical deficiency both in mineralocorticoid and glucocorticoid functions. Indirect immunofluorescence to investigate the presence of circulating autoantibodies against the thyroid and adrenal glands revealed only anti-thyroid antibodies (microsomal pattern) at a dilution of 1:40. Since then, the bitch has been on hydrocortisone and fludrocortisone with no adjustments necessary for a year. The combination of two endocrinopathies and the episodic course of hypoadrenocorticism made the final diagnosis difficult, posed a diagnostic challenge and required the owner's compliance with diagnostic and therapeutic procedures. |
| first_indexed | 2024-04-10T08:02:08Z |
| format | Article |
| id | doaj.art-a6567d128c0d4d758484f4ca356540d0 |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T08:02:08Z |
| publishDate | 2007-09-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-a6567d128c0d4d758484f4ca356540d02023-02-23T03:49:28ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922007-09-0152941942210.17221/1998-VETMEDvet-200709-0006Schmidt's syndrome in a dog: a case reportJ. Pikula0J. Pikulova1H. Bandouchova2P. Hajkova3M. Faldyna4University of Veterinary and Pharmaceutical Sciences, Brno, Czech RepublicAnimal Veterinary Clinic, Kurim, Czech RepublicUniversity of Veterinary and Pharmaceutical Sciences, Brno, Czech RepublicAnimal Veterinary Clinic, Kurim, Czech RepublicUniversity of Veterinary and Pharmaceutical Sciences, Brno, Czech RepublicThis report describes a clinical case and development of the polyglandular failure syndrome including hypothyroidism and hypoadrenocorticism in a 6-year-old female Black Russian Terrier. The bitch was presented because of hypothyroidism on the first occasion. Oral supplementation with sodium levothyroxine resulted in clinical improvement. Four months later, it was presented again with similar and rather vague clinical signs and diagnosed with adrenocortical deficiency both in mineralocorticoid and glucocorticoid functions. Indirect immunofluorescence to investigate the presence of circulating autoantibodies against the thyroid and adrenal glands revealed only anti-thyroid antibodies (microsomal pattern) at a dilution of 1:40. Since then, the bitch has been on hydrocortisone and fludrocortisone with no adjustments necessary for a year. The combination of two endocrinopathies and the episodic course of hypoadrenocorticism made the final diagnosis difficult, posed a diagnostic challenge and required the owner's compliance with diagnostic and therapeutic procedures.https://vetmed.agriculturejournals.cz/artkey/vet-200709-0006_schmidt-s-syndrome-in-a-dog-a-case-report.phppolyglandular failure syndromehypothyroidismhypoadrenocorticism |
| spellingShingle | J. Pikula J. Pikulova H. Bandouchova P. Hajkova M. Faldyna Schmidt's syndrome in a dog: a case report Veterinární Medicína polyglandular failure syndrome hypothyroidism hypoadrenocorticism |
| title | Schmidt's syndrome in a dog: a case report |
| title_full | Schmidt's syndrome in a dog: a case report |
| title_fullStr | Schmidt's syndrome in a dog: a case report |
| title_full_unstemmed | Schmidt's syndrome in a dog: a case report |
| title_short | Schmidt's syndrome in a dog: a case report |
| title_sort | schmidt s syndrome in a dog a case report |
| topic | polyglandular failure syndrome hypothyroidism hypoadrenocorticism |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-200709-0006_schmidt-s-syndrome-in-a-dog-a-case-report.php |
| work_keys_str_mv | AT jpikula schmidtssyndromeinadogacasereport AT jpikulova schmidtssyndromeinadogacasereport AT hbandouchova schmidtssyndromeinadogacasereport AT phajkova schmidtssyndromeinadogacasereport AT mfaldyna schmidtssyndromeinadogacasereport |