Menadione: a platform and a target to valuable compounds synthesis
Naphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that are on the pharmaceutical market for the treatment of various diseases. A special naphthoquinone derivative is menadione, a synthetic naphthoqu...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2022-04-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.18.43 |
| _version_ | 1818468906709286912 |
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| author | Acácio S. de Souza Ruan Carlos B. Ribeiro Dora C. S. Costa Fernanda P. Pauli David R. Pinho Matheus G. de Moraes Fernando de C. da Silva Luana da S. M. Forezi Vitor F. Ferreira |
| author_facet | Acácio S. de Souza Ruan Carlos B. Ribeiro Dora C. S. Costa Fernanda P. Pauli David R. Pinho Matheus G. de Moraes Fernando de C. da Silva Luana da S. M. Forezi Vitor F. Ferreira |
| author_sort | Acácio S. de Souza |
| collection | DOAJ |
| description | Naphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that are on the pharmaceutical market for the treatment of various diseases. A special naphthoquinone derivative is menadione, a synthetic naphthoquinone belonging to the vitamin K group. This compound can be synthesized by different methods and it has a broad range of biological and synthetic applications, which will be highlighted in this review. |
| first_indexed | 2024-04-13T21:17:52Z |
| format | Article |
| id | doaj.art-a65a0e7cf1f54156b6a8fea49046281d |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-04-13T21:17:52Z |
| publishDate | 2022-04-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-a65a0e7cf1f54156b6a8fea49046281d2022-12-22T02:29:37ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972022-04-0118138141910.3762/bjoc.18.431860-5397-18-43Menadione: a platform and a target to valuable compounds synthesisAcácio S. de Souza0Ruan Carlos B. Ribeiro1Dora C. S. Costa2Fernanda P. Pauli3David R. Pinho4Matheus G. de Moraes5Fernando de C. da Silva6Luana da S. M. Forezi7Vitor F. Ferreira8Universidade Federal Fluminense, Departamento de Tecnologia Farmacêutica, Faculdade de Farmácia, R. Dr. Mario Vianna, 523, Santa Rosa, CEP 24241-002, Niterói-RJ, BrazilUniversidade Federal Fluminense, Departamento de Tecnologia Farmacêutica, Faculdade de Farmácia, R. Dr. Mario Vianna, 523, Santa Rosa, CEP 24241-002, Niterói-RJ, BrazilDepartment of Chemistry, CICECO – Aveiro Institute of Materials, University of Aveiro, Campus Universitário de Santiago, 3810-193, Aveiro, PortugalUniversidade Federal Fluminense, Instituto de Química, Departamento de Química Orgânica, 24020-150 Niterói, RJ, BrazilUniversidade Federal Fluminense, Instituto de Química, Departamento de Química Orgânica, 24020-150 Niterói, RJ, BrazilUniversidade Federal Fluminense, Instituto de Química, Departamento de Química Orgânica, 24020-150 Niterói, RJ, BrazilUniversidade Federal Fluminense, Instituto de Química, Departamento de Química Orgânica, 24020-150 Niterói, RJ, BrazilUniversidade Federal Fluminense, Instituto de Química, Departamento de Química Orgânica, 24020-150 Niterói, RJ, BrazilUniversidade Federal Fluminense, Departamento de Tecnologia Farmacêutica, Faculdade de Farmácia, R. Dr. Mario Vianna, 523, Santa Rosa, CEP 24241-002, Niterói-RJ, BrazilNaphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that are on the pharmaceutical market for the treatment of various diseases. A special naphthoquinone derivative is menadione, a synthetic naphthoquinone belonging to the vitamin K group. This compound can be synthesized by different methods and it has a broad range of biological and synthetic applications, which will be highlighted in this review.https://doi.org/10.3762/bjoc.18.43cancerchemical reactions2-methyl-1,4-naphthoquinonequinonesynthetic platformvitamin k |
| spellingShingle | Acácio S. de Souza Ruan Carlos B. Ribeiro Dora C. S. Costa Fernanda P. Pauli David R. Pinho Matheus G. de Moraes Fernando de C. da Silva Luana da S. M. Forezi Vitor F. Ferreira Menadione: a platform and a target to valuable compounds synthesis Beilstein Journal of Organic Chemistry cancer chemical reactions 2-methyl-1,4-naphthoquinone quinone synthetic platform vitamin k |
| title | Menadione: a platform and a target to valuable compounds synthesis |
| title_full | Menadione: a platform and a target to valuable compounds synthesis |
| title_fullStr | Menadione: a platform and a target to valuable compounds synthesis |
| title_full_unstemmed | Menadione: a platform and a target to valuable compounds synthesis |
| title_short | Menadione: a platform and a target to valuable compounds synthesis |
| title_sort | menadione a platform and a target to valuable compounds synthesis |
| topic | cancer chemical reactions 2-methyl-1,4-naphthoquinone quinone synthetic platform vitamin k |
| url | https://doi.org/10.3762/bjoc.18.43 |
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