Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness.
The regulatory logic of time- and tissue-specific gene expression has mostly been dissected in the context of the smallest DNA fragments that, when isolated, recapitulate native expression in reporter assays. It is not known if the genomic sequences surrounding such fragments, often evolutionarily c...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-11-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3213169?pdf=render |