Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities
Two new abietane diterpenoids (<b>1,2</b>), along with five known diterpenoids (<b>3</b>–<b>7</b>), were first isolated and purified from the stems of <i>Clerodendrum bracteatum</i>. The structures of the new compounds were established by extensive ana...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-08-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/16/4870 |
| Summary: | Two new abietane diterpenoids (<b>1,2</b>), along with five known diterpenoids (<b>3</b>–<b>7</b>), were first isolated and purified from the stems of <i>Clerodendrum bracteatum</i>. The structures of the new compounds were established by extensive analysis of mass spectrometric and 1-D, 2-D NMR spectroscopic data. Their antioxidant activities were determined on DPPH radical scavenging and ABTS. The in vitro cytotoxic activities of the compounds were evaluated against the HL-60 and A549 cell lines by the MTT method. |
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| ISSN: | 1420-3049 |