Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities
Two new abietane diterpenoids (<b>1,2</b>), along with five known diterpenoids (<b>3</b>–<b>7</b>), were first isolated and purified from the stems of <i>Clerodendrum bracteatum</i>. The structures of the new compounds were established by extensive ana...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/16/4870 |
| _version_ | 1797522725100584960 |
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| author | Pingting Li Lingling Li Qin Zhu Mingfeng Xu |
| author_facet | Pingting Li Lingling Li Qin Zhu Mingfeng Xu |
| author_sort | Pingting Li |
| collection | DOAJ |
| description | Two new abietane diterpenoids (<b>1,2</b>), along with five known diterpenoids (<b>3</b>–<b>7</b>), were first isolated and purified from the stems of <i>Clerodendrum bracteatum</i>. The structures of the new compounds were established by extensive analysis of mass spectrometric and 1-D, 2-D NMR spectroscopic data. Their antioxidant activities were determined on DPPH radical scavenging and ABTS. The in vitro cytotoxic activities of the compounds were evaluated against the HL-60 and A549 cell lines by the MTT method. |
| first_indexed | 2024-03-10T08:33:26Z |
| format | Article |
| id | doaj.art-a65f71d7b62b4d66a538ab26860bab25 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T08:33:26Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-a65f71d7b62b4d66a538ab26860bab252023-11-22T08:53:08ZengMDPI AGMolecules1420-30492021-08-012616487010.3390/molecules26164870Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic ActivitiesPingting Li0Lingling Li1Qin Zhu2Mingfeng Xu3College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, ChinaTwo new abietane diterpenoids (<b>1,2</b>), along with five known diterpenoids (<b>3</b>–<b>7</b>), were first isolated and purified from the stems of <i>Clerodendrum bracteatum</i>. The structures of the new compounds were established by extensive analysis of mass spectrometric and 1-D, 2-D NMR spectroscopic data. Their antioxidant activities were determined on DPPH radical scavenging and ABTS. The in vitro cytotoxic activities of the compounds were evaluated against the HL-60 and A549 cell lines by the MTT method.https://www.mdpi.com/1420-3049/26/16/4870<i>Clerodendrum bracteatum</i>abietane diterpeneantioxidant activitycytotoxic activity |
| spellingShingle | Pingting Li Lingling Li Qin Zhu Mingfeng Xu Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities Molecules <i>Clerodendrum bracteatum</i> abietane diterpene antioxidant activity cytotoxic activity |
| title | Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities |
| title_full | Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities |
| title_fullStr | Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities |
| title_full_unstemmed | Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities |
| title_short | Abietane Diterpenoids Isolated from <i>Clerodendrum bracteatum</i> and Their Antioxidant and Cytotoxic Activities |
| title_sort | abietane diterpenoids isolated from i clerodendrum bracteatum i and their antioxidant and cytotoxic activities |
| topic | <i>Clerodendrum bracteatum</i> abietane diterpene antioxidant activity cytotoxic activity |
| url | https://www.mdpi.com/1420-3049/26/16/4870 |
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