Granular cell tumors: a report of six cases

<p>Abstract</p> <p>Granular cell tumor is a soft tissue neoplasm that originates in the nervous system and arises at virtually any body site, but is mainly found in the skin, oral cavity or digestive tract. Most are benign and reportedly malignant cases are rare, occurring in only...

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Main Authors: Aoyama Kei, Kamio Takako, Hirano Azusa, Seshimo Akiyoshi, Kameoka Shingo
Format: Article
Language:English
Published: BMC 2012-09-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:http://www.wjso.com/content/10/1/204
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author Aoyama Kei
Kamio Takako
Hirano Azusa
Seshimo Akiyoshi
Kameoka Shingo
author_facet Aoyama Kei
Kamio Takako
Hirano Azusa
Seshimo Akiyoshi
Kameoka Shingo
author_sort Aoyama Kei
collection DOAJ
description <p>Abstract</p> <p>Granular cell tumor is a soft tissue neoplasm that originates in the nervous system and arises at virtually any body site, but is mainly found in the skin, oral cavity or digestive tract. Most are benign and reportedly malignant cases are rare, occurring in only 1% or 2% of cases. We report on our findings in six patients who developed granular cell tumor in the mammary gland, esophagus, subcutaneous tissue and muscle. Of six patients, two had granular cell tumor located in the breast, two in the submucosa of the esophagus, and the other two under the skin of the left axillary cavity and in the right latissimus dorsi muscle, respectively. One of the two patients with tumor in the submucosa of the esophagus also had esophageal cancer. Patients’ age ranged from 41 to 70 years (average, 59.1 years). Two patients with tumor in the submucosa of the esophagus were men, and the others were women. All of them were given a diagnosis of granular cell tumor by tissue biopsy and examination of excised specimens, but no evidence of malignancy was found. No recurrence has been noted in the patients who underwent surgical tumor removal.</p>
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spelling doaj.art-a6665d9300054f8599c29d635e07a5ea2022-12-22T01:20:59ZengBMCWorld Journal of Surgical Oncology1477-78192012-09-0110120410.1186/1477-7819-10-204Granular cell tumors: a report of six casesAoyama KeiKamio TakakoHirano AzusaSeshimo AkiyoshiKameoka Shingo<p>Abstract</p> <p>Granular cell tumor is a soft tissue neoplasm that originates in the nervous system and arises at virtually any body site, but is mainly found in the skin, oral cavity or digestive tract. Most are benign and reportedly malignant cases are rare, occurring in only 1% or 2% of cases. We report on our findings in six patients who developed granular cell tumor in the mammary gland, esophagus, subcutaneous tissue and muscle. Of six patients, two had granular cell tumor located in the breast, two in the submucosa of the esophagus, and the other two under the skin of the left axillary cavity and in the right latissimus dorsi muscle, respectively. One of the two patients with tumor in the submucosa of the esophagus also had esophageal cancer. Patients’ age ranged from 41 to 70 years (average, 59.1 years). Two patients with tumor in the submucosa of the esophagus were men, and the others were women. All of them were given a diagnosis of granular cell tumor by tissue biopsy and examination of excised specimens, but no evidence of malignancy was found. No recurrence has been noted in the patients who underwent surgical tumor removal.</p>http://www.wjso.com/content/10/1/204Granular cell tumor
spellingShingle Aoyama Kei
Kamio Takako
Hirano Azusa
Seshimo Akiyoshi
Kameoka Shingo
Granular cell tumors: a report of six cases
World Journal of Surgical Oncology
Granular cell tumor
title Granular cell tumors: a report of six cases
title_full Granular cell tumors: a report of six cases
title_fullStr Granular cell tumors: a report of six cases
title_full_unstemmed Granular cell tumors: a report of six cases
title_short Granular cell tumors: a report of six cases
title_sort granular cell tumors a report of six cases
topic Granular cell tumor
url http://www.wjso.com/content/10/1/204
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AT kamiotakako granularcelltumorsareportofsixcases
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AT seshimoakiyoshi granularcelltumorsareportofsixcases
AT kameokashingo granularcelltumorsareportofsixcases