Approach to the Patients with Elevated CA 19-9

With the widespread adoption of health check-ups, tumor markers are being used for screening healthy individuals without symptoms related to cancer. Although CA 19-9 is known to have diagnostic value when a patient presents with symptoms, the evidence for its clinical value as a cancer screening tes...

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Main Author: Jung Wan Choe
Format: Article
Language:English
Published: Jin Publishing & Printing Co. 2023-05-01
Series:The Korean Journal of Gastroenterology
Subjects:
Online Access:https://www.kjg.or.kr/journal/view.html?uid=5913&vmd=Full
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author Jung Wan Choe
author_facet Jung Wan Choe
author_sort Jung Wan Choe
collection DOAJ
description With the widespread adoption of health check-ups, tumor markers are being used for screening healthy individuals without symptoms related to cancer. Although CA 19-9 is known to have diagnostic value when a patient presents with symptoms, the evidence for its clinical value as a cancer screening test in asymptomatic patients is still lacking. However, patients who experience an increase in CA 19-9 levels may feel anxious about the possibility of having cancer and may seek medical attention. If the CA 19-9 level is elevated, it may be necessary to consider initial testing for malignant tumors of the pancreas. It should be recognized that the level can also increase in malignant tumors of the gastrointestinal tract, thyroid, and reproductive organs. Since the CA 19-9 levels can also increase in various benign diseases, it is important to evaluate if there is an underlying benign disease through appropriate testing and follow-up to reduce patient anxiety and discontinue unnecessary follow-up tests.
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spelling doaj.art-a668f851d2544411ba833ea98c8cd8ce2024-03-13T06:36:02ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692023-05-0181518518810.4166/kjg.2023.042Approach to the Patients with Elevated CA 19-9Jung Wan Choe0https://orcid.org/0000-0003-0634-5141Division of Gastroenterology, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, KoreaWith the widespread adoption of health check-ups, tumor markers are being used for screening healthy individuals without symptoms related to cancer. Although CA 19-9 is known to have diagnostic value when a patient presents with symptoms, the evidence for its clinical value as a cancer screening test in asymptomatic patients is still lacking. However, patients who experience an increase in CA 19-9 levels may feel anxious about the possibility of having cancer and may seek medical attention. If the CA 19-9 level is elevated, it may be necessary to consider initial testing for malignant tumors of the pancreas. It should be recognized that the level can also increase in malignant tumors of the gastrointestinal tract, thyroid, and reproductive organs. Since the CA 19-9 levels can also increase in various benign diseases, it is important to evaluate if there is an underlying benign disease through appropriate testing and follow-up to reduce patient anxiety and discontinue unnecessary follow-up tests.https://www.kjg.or.kr/journal/view.html?uid=5913&vmd=Fullca-19-9 antigentumorpancreatic diseasesbiliary tract diseasesgastrointestinal diseases
spellingShingle Jung Wan Choe
Approach to the Patients with Elevated CA 19-9
The Korean Journal of Gastroenterology
ca-19-9 antigen
tumor
pancreatic diseases
biliary tract diseases
gastrointestinal diseases
title Approach to the Patients with Elevated CA 19-9
title_full Approach to the Patients with Elevated CA 19-9
title_fullStr Approach to the Patients with Elevated CA 19-9
title_full_unstemmed Approach to the Patients with Elevated CA 19-9
title_short Approach to the Patients with Elevated CA 19-9
title_sort approach to the patients with elevated ca 19 9
topic ca-19-9 antigen
tumor
pancreatic diseases
biliary tract diseases
gastrointestinal diseases
url https://www.kjg.or.kr/journal/view.html?uid=5913&vmd=Full
work_keys_str_mv AT jungwanchoe approachtothepatientswithelevatedca199