Application of droplet digital PCR in minimal residual disease monitoring of rare fusion transcripts and mutations in haematological malignancies

Application of droplet digital PCR in minimal residual disease monitoring of rare fusion transcripts and mutations in haematological malignancies

Abstract Leukaemia of various subtypes are driven by distinct chromosomal rearrangement or genetic abnormalities. The leukaemogenic fusion transcripts or genetic mutations serve as molecular markers for minimal residual disease (MRD) monitoring. The current study evaluated the applicability of sever...

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Bibliographic Details
Main Authors: Beca B. K. Ip, Anthony T. C. Wong, Janet Hei Yin Law, Chun Hang Au, Shing Yan Ma, James C. S. Chim, Raymond H. S. Liang, Anskar Y. H. Leung, Thomas S. K. Wan, Edmond S. K. Ma
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57016-y

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