Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species
DNA methylation is involved in regulatory processes throughout the animal kingdom. Here, the authors map DNA methylation in 535 vertebrates and 45 invertebrates, establishing a reference dataset for cross-species analysis and exploring epigenetic variation across vertebrate evolution.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34828-y |
| _version_ | 1811177021821157376 |
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| author | Johanna Klughammer Daria Romanovskaia Amelie Nemc Annika Posautz Charlotte A. Seid Linda C. Schuster Melissa C. Keinath Juan Sebastian Lugo Ramos Lindsay Kosack Ann Evankow Dieter Printz Stefanie Kirchberger Bekir Ergüner Paul Datlinger Nikolaus Fortelny Christian Schmidl Matthias Farlik Kaja Skjærven Andreas Bergthaler Miriam Liedvogel Denise Thaller Pamela A. Burger Marcela Hermann Martin Distel Daniel L. Distel Anna Kübber-Heiss Christoph Bock |
| author_facet | Johanna Klughammer Daria Romanovskaia Amelie Nemc Annika Posautz Charlotte A. Seid Linda C. Schuster Melissa C. Keinath Juan Sebastian Lugo Ramos Lindsay Kosack Ann Evankow Dieter Printz Stefanie Kirchberger Bekir Ergüner Paul Datlinger Nikolaus Fortelny Christian Schmidl Matthias Farlik Kaja Skjærven Andreas Bergthaler Miriam Liedvogel Denise Thaller Pamela A. Burger Marcela Hermann Martin Distel Daniel L. Distel Anna Kübber-Heiss Christoph Bock |
| author_sort | Johanna Klughammer |
| collection | DOAJ |
| description | DNA methylation is involved in regulatory processes throughout the animal kingdom. Here, the authors map DNA methylation in 535 vertebrates and 45 invertebrates, establishing a reference dataset for cross-species analysis and exploring epigenetic variation across vertebrate evolution. |
| first_indexed | 2024-04-10T21:01:14Z |
| format | Article |
| id | doaj.art-a66c803083214c8fba3343238e70ba59 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-10T21:01:14Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-a66c803083214c8fba3343238e70ba592023-01-22T12:18:19ZengNature PortfolioNature Communications2041-17232023-01-0114112310.1038/s41467-022-34828-yComparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal speciesJohanna Klughammer0Daria Romanovskaia1Amelie Nemc2Annika Posautz3Charlotte A. Seid4Linda C. Schuster5Melissa C. Keinath6Juan Sebastian Lugo Ramos7Lindsay Kosack8Ann Evankow9Dieter Printz10Stefanie Kirchberger11Bekir Ergüner12Paul Datlinger13Nikolaus Fortelny14Christian Schmidl15Matthias Farlik16Kaja Skjærven17Andreas Bergthaler18Miriam Liedvogel19Denise Thaller20Pamela A. Burger21Marcela Hermann22Martin Distel23Daniel L. Distel24Anna Kübber-Heiss25Christoph Bock26CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesResearch Institute of Wildlife Ecology, University of Veterinary Medicine ViennaOcean Genome Legacy Center, Northeastern University Marine Science CenterCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesDepartment of Biology, University of KentuckyMax Planck Research Group Behavioral Genomics, Max Planck Institute for Evolutionary BiologyCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesOcean Genome Legacy Center, Northeastern University Marine Science CenterChildren’s Cancer Research Institute, St. Anna KinderkrebsforschungChildren’s Cancer Research Institute, St. Anna KinderkrebsforschungCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesInstitute of Marine Research (IMR)CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesMax Planck Research Group Behavioral Genomics, Max Planck Institute for Evolutionary BiologyDepartment for Pathobiology, University of Veterinary Medicine ViennaResearch Institute of Wildlife Ecology, University of Veterinary Medicine ViennaMedical University of Vienna, Department of Medical BiochemistryChildren’s Cancer Research Institute, St. Anna KinderkrebsforschungOcean Genome Legacy Center, Northeastern University Marine Science CenterResearch Institute of Wildlife Ecology, University of Veterinary Medicine ViennaCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesDNA methylation is involved in regulatory processes throughout the animal kingdom. Here, the authors map DNA methylation in 535 vertebrates and 45 invertebrates, establishing a reference dataset for cross-species analysis and exploring epigenetic variation across vertebrate evolution.https://doi.org/10.1038/s41467-022-34828-y |
| spellingShingle | Johanna Klughammer Daria Romanovskaia Amelie Nemc Annika Posautz Charlotte A. Seid Linda C. Schuster Melissa C. Keinath Juan Sebastian Lugo Ramos Lindsay Kosack Ann Evankow Dieter Printz Stefanie Kirchberger Bekir Ergüner Paul Datlinger Nikolaus Fortelny Christian Schmidl Matthias Farlik Kaja Skjærven Andreas Bergthaler Miriam Liedvogel Denise Thaller Pamela A. Burger Marcela Hermann Martin Distel Daniel L. Distel Anna Kübber-Heiss Christoph Bock Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species Nature Communications |
| title | Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species |
| title_full | Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species |
| title_fullStr | Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species |
| title_full_unstemmed | Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species |
| title_short | Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species |
| title_sort | comparative analysis of genome scale base resolution dna methylation profiles across 580 animal species |
| url | https://doi.org/10.1038/s41467-022-34828-y |
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