Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity

ABSTRACT: Since the first monkeypox (MPX) case was reported in humans in 1970, there have been several outbreaks of the disease. MPX is endemic in central and western Africa. MPX virus infection is confirmed using the conventional polymerase chain reaction, which detects the viral DNA in samples fro...

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Main Authors: Enos Moyo, Godfrey Musuka, Grant Murewanhema, Perseverance Moyo, Tafadzwa Dzinamarira
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971222004866
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author Enos Moyo
Godfrey Musuka
Grant Murewanhema
Perseverance Moyo
Tafadzwa Dzinamarira
author_facet Enos Moyo
Godfrey Musuka
Grant Murewanhema
Perseverance Moyo
Tafadzwa Dzinamarira
author_sort Enos Moyo
collection DOAJ
description ABSTRACT: Since the first monkeypox (MPX) case was reported in humans in 1970, there have been several outbreaks of the disease. MPX is endemic in central and western Africa. MPX virus infection is confirmed using the conventional polymerase chain reaction, which detects the viral DNA in samples from the rash. Of concern is that the current outbreak has affected five regions of the world. Although MPX confirmatory tests are available worldwide, there are concerns about Africa's capacity to diagnose and contain the disease. The challenges faced by Africa include a lack of adequate laboratory infrastructure and health care workers, weak disease surveillance systems, and a lack of MPX knowledge among health care workers and communities. These challenges can be addressed by mobilizing resources for MPX virus testing, strengthening surveillance systems, collaboration among countries, training health care workers, task shifting, and engaging communities.
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spelling doaj.art-a67285f343fa4f50b60cb82304f146592022-12-22T03:12:18ZengElsevierInternational Journal of Infectious Diseases1201-97122022-10-01123127130Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacityEnos Moyo0Godfrey Musuka1Grant Murewanhema2Perseverance Moyo3Tafadzwa Dzinamarira4Medical Centre Oshakati, Oshakati, NamibiaInternational Initiative for Impact Evaluation, Harare, ZimbabweUniversity of Zimbabwe, Harare, ZimbabweMedical Centre Oshakati, Oshakati, NamibiaICAP at Columbia University, Kigali, Rwanda; Corresponding author: Tafadzwa Dzinamarira, ICAP at Columbia University, Kigali, Rwanda.ABSTRACT: Since the first monkeypox (MPX) case was reported in humans in 1970, there have been several outbreaks of the disease. MPX is endemic in central and western Africa. MPX virus infection is confirmed using the conventional polymerase chain reaction, which detects the viral DNA in samples from the rash. Of concern is that the current outbreak has affected five regions of the world. Although MPX confirmatory tests are available worldwide, there are concerns about Africa's capacity to diagnose and contain the disease. The challenges faced by Africa include a lack of adequate laboratory infrastructure and health care workers, weak disease surveillance systems, and a lack of MPX knowledge among health care workers and communities. These challenges can be addressed by mobilizing resources for MPX virus testing, strengthening surveillance systems, collaboration among countries, training health care workers, task shifting, and engaging communities.http://www.sciencedirect.com/science/article/pii/S1201971222004866MonkeypoxDiagnosisContainmentAfrica
spellingShingle Enos Moyo
Godfrey Musuka
Grant Murewanhema
Perseverance Moyo
Tafadzwa Dzinamarira
Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
International Journal of Infectious Diseases
Monkeypox
Diagnosis
Containment
Africa
title Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_full Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_fullStr Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_full_unstemmed Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_short Monkeypox outbreak: a perspective on Africa's diagnostic and containment capacity
title_sort monkeypox outbreak a perspective on africa s diagnostic and containment capacity
topic Monkeypox
Diagnosis
Containment
Africa
url http://www.sciencedirect.com/science/article/pii/S1201971222004866
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AT perseverancemoyo monkeypoxoutbreakaperspectiveonafricasdiagnosticandcontainmentcapacity
AT tafadzwadzinamarira monkeypoxoutbreakaperspectiveonafricasdiagnosticandcontainmentcapacity