CD147 induces asthmatic airway remodeling and activation of circulating fibrocytes in a mouse model of asthma

CD147 induces asthmatic airway remodeling and activation of circulating fibrocytes in a mouse model of asthma

Abstract Background Airway remodeling is a poorly reversible feature of asthma which lacks effective therapeutic interventions. CD147 can regulate extracellular matrix (ECM) remodeling and tissue fibrosis, and participate in the pathogenesis of asthma. In this study, the role of CD147 in airway remo...

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Bibliographic Details
Main Authors: Zhao Li, Tao Cheng, Yaning Guo, Rong Gao, Xuankun Ma, Xuecong Mao, Xinpeng Han
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Respiratory Research
Subjects:
Asthma
CD147
Airway remodeling
Circulating fibrocytes
Online Access:https://doi.org/10.1186/s12931-023-02646-5

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