In leukemia, knock-down of the death inducer-obliterator gene would inhibit the proliferation of endothelial cells by inhibiting the expression of CDK6 and CCND1

In leukemia, knock-down of the death inducer-obliterator gene would inhibit the proliferation of endothelial cells by inhibiting the expression of CDK6 and CCND1

Background Endothelial cells (ECs) are a critical component of the hematopoietic niche, and the cross-talk between ECs and leukemia was reported recently. This study aimed to determine the genes involved in the proliferation inhibition of endothelial cells in leukemia. Methods Human umbilical vein e...

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Bibliographic Details
Main Authors: Honghua Cao, Lilan Wang, Chengkui Geng, Man Yang, Wenwen Mao, Linlin Yang, Yin Ma, Ming He, Yeying Zhou, Lianqing Liu, Xuejiao Hu, Jingxing Yu, Xiufen Shen, Xuezhong Gu, Liefen Yin, Zhenglei Shen
Format: Article
Language:English
Published: PeerJ Inc. 2022-02-01
Series:PeerJ
Subjects:
Leukemia
Endothelial cells
CDK6
CCND1
DIDO
Online Access:https://peerj.com/articles/12832.pdf

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