Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice.
The world health organization estimates that more than a quarter of the human population is infected with parasitic worms that are called helminths. Many helminths suppress the immune system of their hosts to prolong their survival. This helminth-induced immunosuppression "spills over" to...
Main Authors: | Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Gülsah Gabriel, Minka Breloer |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0266456 |
Similar Items
-
A Combination of Deworming and Prime-Boost Vaccination Regimen Restores Efficacy of Vaccination Against Influenza in Helminth-Infected Mice
by: Nadine Stetter, et al.
Published: (2021-12-01) -
Helminth Infections Suppress the Efficacy of Vaccination against Seasonal Influenza
by: Wiebke Hartmann, et al.
Published: (2019-11-01) -
Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti.
by: Martina Reitz, et al.
Published: (2018-11-01) -
Nematode-induced interference with vaccination efficacy targets follicular T helper cell induction and is preserved after termination of infection.
by: Irma Haben, et al.
Published: (2014-09-01) -
Eosinophils and Neutrophils Eliminate Migrating Strongyloides ratti Larvae at the Site of Infection in the Context of Extracellular DNA Trap Formation
by: Alexandra Ehrens, et al.
Published: (2021-08-01)