Essentially all excess fibroblast cholesterol moves from plasma membranes to intracellular compartments.
It has been shown that modestly increasing plasma membrane cholesterol beyond its physiological set point greatly increases the endoplasmic reticulum and mitochondrial pools, thereby eliciting manifold feedback responses that return cell cholesterol to its resting state. The question arises whether...
Main Authors: | Yvonne Lange, Jin Ye, Theodore L Steck |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4094430?pdf=render |
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