n-3 polyunsaturated fatty acids delay intervertebral disc degeneration by inhibiting nuclear receptor coactivator 4-mediated iron overload

n-3 polyunsaturated fatty acids delay intervertebral disc degeneration by inhibiting nuclear receptor coactivator 4-mediated iron overload

Summary: n-3 polyunsaturated fatty acids (PUFAs) are closely related to the progression of numerous chronic inflammatory diseases, but the role of n-3 PUFAs in the intervertebral disc degeneration (IVDD) remains unclear. In this study, male C57BL/6 wildtype mice (WT group, n = 30) and fat-1 transgen...

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Bibliographic Details
Main Authors: Xiang Ao, Tao Jiang, Yuan Li, Weiyi Lai, Zhengnan Lian, Liang Wang, Minjun Huang, Zhongmin Zhang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Pharmacology
Natural sciences
Biological sciences
Physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223027980

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223027980

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