Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis

Objective To compare the perioperative morbidity of 2-level anterior cervical discectomy and fusion (ACDF) with that of 1-level anterior cervical corpectomy and fusion (ACCF) for the treatment of cervical degenerative conditions. Methods A retrospective study of the 2005–2016 National Surgical Quali...

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Main Authors: Anoop R. Galivanche, Raj Gala, Preetpaul S. Bagi, Arianne J. Boylan, Christopher M. Dussik, Pedro D. Coutinho, Jonathan N. Grauer, Arya G. Varthi
Format: Article
Language:English
Published: Korean Spinal Neurosurgery Society 2020-12-01
Series:Neurospine
Subjects:
Online Access:http://www.e-neurospine.org/upload/pdf/ns-2040134-067.pdf
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author Anoop R. Galivanche
Raj Gala
Preetpaul S. Bagi
Arianne J. Boylan
Christopher M. Dussik
Pedro D. Coutinho
Jonathan N. Grauer
Arya G. Varthi
author_facet Anoop R. Galivanche
Raj Gala
Preetpaul S. Bagi
Arianne J. Boylan
Christopher M. Dussik
Pedro D. Coutinho
Jonathan N. Grauer
Arya G. Varthi
author_sort Anoop R. Galivanche
collection DOAJ
description Objective To compare the perioperative morbidity of 2-level anterior cervical discectomy and fusion (ACDF) with that of 1-level anterior cervical corpectomy and fusion (ACCF) for the treatment of cervical degenerative conditions. Methods A retrospective study of the 2005–2016 National Surgical Quality Improvement Program database for patients undergoing 2-level ACDF and 1-level ACCF was performed. Patient data included: age, sex, body mass index (BMI), functional status, and American Society of Anesthesiologists (ASA) physical status (PS) classification. Hospital data included: operative time and length of hospital stay (LOS). Thirty-day outcome data included: any, serious, and minor adverse events, return to the operating room, readmission, and mortality. After propensity matching for age, sex, ASA PS classification, functional status, and BMI, multivariate logistic regression analysis was used to compare outcomes between the 2 propensity-matched subcohorts. Finally, multivariate logistic regression that additionally controlled for operative time was performed to compare the 2 propensity-matched subcohorts. Results A total of 17,497 cases were identified, with 90.20% undergoing 2-level ACDF and 9.80% undergoing 1-level ACCF. Patients undergoing 2-level ACDF were younger, more likely to be female, had higher functional status, and had shorter operative time and LOS (p < 0.001). After propensity score matching, cases undergoing 1-level ACCF had a statistically significant higher rate of serious adverse events (p = 0.005). This difference was no longer significant after controlling for operative time. Conclusion While there was noted to be additional morbidity in 1-level ACCF cases relative to 2-level ACDF cases, the lack of difference once controlling for the surgical time supports using the procedure that best accomplishes the surgical objectives.
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spelling doaj.art-a68029a076924535b545b5da519abc142024-02-02T12:05:03ZengKorean Spinal Neurosurgery SocietyNeurospine2586-65832586-65912020-12-0117487187810.14245/ns.2040134.0671092Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program AnalysisAnoop R. Galivanche0Raj Gala1Preetpaul S. Bagi2Arianne J. Boylan3Christopher M. Dussik4Pedro D. Coutinho5Jonathan N. Grauer6Arya G. Varthi7 Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USAObjective To compare the perioperative morbidity of 2-level anterior cervical discectomy and fusion (ACDF) with that of 1-level anterior cervical corpectomy and fusion (ACCF) for the treatment of cervical degenerative conditions. Methods A retrospective study of the 2005–2016 National Surgical Quality Improvement Program database for patients undergoing 2-level ACDF and 1-level ACCF was performed. Patient data included: age, sex, body mass index (BMI), functional status, and American Society of Anesthesiologists (ASA) physical status (PS) classification. Hospital data included: operative time and length of hospital stay (LOS). Thirty-day outcome data included: any, serious, and minor adverse events, return to the operating room, readmission, and mortality. After propensity matching for age, sex, ASA PS classification, functional status, and BMI, multivariate logistic regression analysis was used to compare outcomes between the 2 propensity-matched subcohorts. Finally, multivariate logistic regression that additionally controlled for operative time was performed to compare the 2 propensity-matched subcohorts. Results A total of 17,497 cases were identified, with 90.20% undergoing 2-level ACDF and 9.80% undergoing 1-level ACCF. Patients undergoing 2-level ACDF were younger, more likely to be female, had higher functional status, and had shorter operative time and LOS (p < 0.001). After propensity score matching, cases undergoing 1-level ACCF had a statistically significant higher rate of serious adverse events (p = 0.005). This difference was no longer significant after controlling for operative time. Conclusion While there was noted to be additional morbidity in 1-level ACCF cases relative to 2-level ACDF cases, the lack of difference once controlling for the surgical time supports using the procedure that best accomplishes the surgical objectives.http://www.e-neurospine.org/upload/pdf/ns-2040134-067.pdfanterior cervical discectomy and fusionanterior cervical corpectomy and fusioncorpectomydiscectomyfusion
spellingShingle Anoop R. Galivanche
Raj Gala
Preetpaul S. Bagi
Arianne J. Boylan
Christopher M. Dussik
Pedro D. Coutinho
Jonathan N. Grauer
Arya G. Varthi
Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
Neurospine
anterior cervical discectomy and fusion
anterior cervical corpectomy and fusion
corpectomy
discectomy
fusion
title Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
title_full Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
title_fullStr Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
title_full_unstemmed Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
title_short Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
title_sort perioperative outcomes in 17 947 patients undergoing 2 level anterior cervical discectomy and fusion versus 1 level anterior cervical corpectomy for treatment of cervical degenerative conditions a propensity score matched national surgical quality improvement program analysis
topic anterior cervical discectomy and fusion
anterior cervical corpectomy and fusion
corpectomy
discectomy
fusion
url http://www.e-neurospine.org/upload/pdf/ns-2040134-067.pdf
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