A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant
Background: Pharyngeal-cervical-brachial (PCB) variant is a rare form of Guillan-Barre Syndrome (GBS). Antibodies against other membrane proteins like GM1b and GD1a have been found only in a small number of patients with Guillan Barre syndrome variant. Case Report: Here, we report a 5.5 year-old...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2013-09-01
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| Series: | Balkan Medical Journal |
| Subjects: | |
| Online Access: | http://balkanmedicaljournal.org/text.php?lang=en&id=378 |
| _version_ | 1797906186057547776 |
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| author | Metin Uysalol Burak Tatlı Erhan Aygün Semra Kayaoğlu Nedret Uzel Agop Çıtak |
| author_facet | Metin Uysalol Burak Tatlı Erhan Aygün Semra Kayaoğlu Nedret Uzel Agop Çıtak |
| author_sort | Metin Uysalol |
| collection | DOAJ |
| description | Background: Pharyngeal-cervical-brachial (PCB) variant is a rare form of Guillan-Barre Syndrome (GBS). Antibodies against other membrane proteins like GM1b and GD1a have been found only in a small number of patients with Guillan Barre syndrome variant.
Case Report: Here, we report a 5.5 year-old boy diagnosed early with positive GD1a and GD1b gangliosides of Guillan-Barre syndrome pharyngeal cervical-Brachial variant, who improved and recovered fully in a short period. This is in contrast to those whose recovery period prolongs in spite of early diagnosis and appropriate treatment and/or those who experience incomplete recovery.
Conclusion: In summary, diagnosis of PCB variant of GBS should be considered in infants with sudden onset bulbar symptoms and muscle weakness, and it should be kept in mind that early diagnosis and appropriate treatment can give successful outcomes. |
| first_indexed | 2024-04-10T10:17:03Z |
| format | Article |
| id | doaj.art-a681176c4c244ff09ffc62c6a13c98ed |
| institution | Directory Open Access Journal |
| issn | 2146-3123 2146-3131 |
| language | English |
| last_indexed | 2024-04-10T10:17:03Z |
| publishDate | 2013-09-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Balkan Medical Journal |
| spelling | doaj.art-a681176c4c244ff09ffc62c6a13c98ed2023-02-15T16:21:49ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312013-09-0130333734110.5152/balkanmedj.2013.8334A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial VariantMetin Uysalol0Burak Tatlı1Erhan Aygün2Semra Kayaoğlu3Nedret Uzel4Agop Çıtak5Department of Pediatrics, İstanbul University İstanbul Faculty of Medicine, İstanbul, TurkeyDepartment of Pediatrics, İstanbul University İstanbul Faculty of Medicine, İstanbul, TurkeyDepartment of Pediatrics, İstanbul University İstanbul Faculty of Medicine, İstanbul, TurkeyDepartment of Pediatrics, Şişli Etfal Training and Research Hospital, İstanbul, TurkeyDepartment of Pediatrics, İstanbul University İstanbul Faculty of Medicine, İstanbul, TurkeyDepartment of Pediatrics, İstanbul University İstanbul Faculty of Medicine, İstanbul, TurkeyBackground: Pharyngeal-cervical-brachial (PCB) variant is a rare form of Guillan-Barre Syndrome (GBS). Antibodies against other membrane proteins like GM1b and GD1a have been found only in a small number of patients with Guillan Barre syndrome variant. Case Report: Here, we report a 5.5 year-old boy diagnosed early with positive GD1a and GD1b gangliosides of Guillan-Barre syndrome pharyngeal cervical-Brachial variant, who improved and recovered fully in a short period. This is in contrast to those whose recovery period prolongs in spite of early diagnosis and appropriate treatment and/or those who experience incomplete recovery. Conclusion: In summary, diagnosis of PCB variant of GBS should be considered in infants with sudden onset bulbar symptoms and muscle weakness, and it should be kept in mind that early diagnosis and appropriate treatment can give successful outcomes.http://balkanmedicaljournal.org/text.php?lang=en&id=378Guillain-Barré syndromepharyngeal-cervical-brachial variantganglioside antibodieschildrenemergency department |
| spellingShingle | Metin Uysalol Burak Tatlı Erhan Aygün Semra Kayaoğlu Nedret Uzel Agop Çıtak A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant Balkan Medical Journal Guillain-Barré syndrome pharyngeal-cervical-brachial variant ganglioside antibodies children emergency department |
| title | A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant |
| title_full | A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant |
| title_fullStr | A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant |
| title_full_unstemmed | A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant |
| title_short | A Rare Form of Guillan Barre Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant |
| title_sort | rare form of guillan barre syndrome a child diagnosed with anti gd1a and anti gd1b positive pharyngeal cervical brachial variant |
| topic | Guillain-Barré syndrome pharyngeal-cervical-brachial variant ganglioside antibodies children emergency department |
| url | http://balkanmedicaljournal.org/text.php?lang=en&id=378 |
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