Efficiency of Immunonutrition in Surgical Cancer Patients

The enteral diet enriched with arginine, glutamine, omega-3 fatty acids and nucleotides named as immunonutrition reduce the duration of hospital stay after surgery, infectious complications and the risk of morbidity. These nutrients modulate inflammatory response, intestinal and immunological functi...

Full description

Bibliographic Details
Main Authors: Pelin Polat, M. Merve Tengillimoğlu Metin, Mevlüde Kızıl
Format: Article
Language:English
Published: Hacettepe University 2019-03-01
Series:Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/324280
_version_ 1828012934924599296
author Pelin Polat
M. Merve Tengillimoğlu Metin
Mevlüde Kızıl
author_facet Pelin Polat
M. Merve Tengillimoğlu Metin
Mevlüde Kızıl
author_sort Pelin Polat
collection DOAJ
description The enteral diet enriched with arginine, glutamine, omega-3 fatty acids and nucleotides named as immunonutrition reduce the duration of hospital stay after surgery, infectious complications and the risk of morbidity. These nutrients modulate inflammatory response, intestinal and immunological functions. The immune system is the primary defense against pathogenic microorganisms and cancer cells. The release of proinflammatory cytokines, the formation of reactive oxygen nitrogen species are required for the inflammatory response. Regulation of the immune system with dietary components has become as an important additional therapy in cancer patients. Although there are randomized controlled trials showing positive effects of immunonutrients in serious diseases such as trauma or burn, there is no strong evidence for these effects in cancer patients. Further prospective studies are needed to demonstrate beneficial effects of immunonutrition in cancer patients. In this review, studies evaluating the efficacy of immunonutrition in cancer patients are summarized.
first_indexed 2024-04-10T09:39:56Z
format Article
id doaj.art-a6826a9ddd0e456c8bb5e0c3cdd1323f
institution Directory Open Access Journal
issn 2528-9918
language English
last_indexed 2024-04-10T09:39:56Z
publishDate 2019-03-01
publisher Hacettepe University
record_format Article
series Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi
spelling doaj.art-a6826a9ddd0e456c8bb5e0c3cdd1323f2023-02-17T12:44:27ZengHacettepe UniversityHacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi2528-99182019-03-0133116Efficiency of Immunonutrition in Surgical Cancer PatientsPelin Polat M. Merve Tengillimoğlu MetinMevlüde KızılThe enteral diet enriched with arginine, glutamine, omega-3 fatty acids and nucleotides named as immunonutrition reduce the duration of hospital stay after surgery, infectious complications and the risk of morbidity. These nutrients modulate inflammatory response, intestinal and immunological functions. The immune system is the primary defense against pathogenic microorganisms and cancer cells. The release of proinflammatory cytokines, the formation of reactive oxygen nitrogen species are required for the inflammatory response. Regulation of the immune system with dietary components has become as an important additional therapy in cancer patients. Although there are randomized controlled trials showing positive effects of immunonutrients in serious diseases such as trauma or burn, there is no strong evidence for these effects in cancer patients. Further prospective studies are needed to demonstrate beneficial effects of immunonutrition in cancer patients. In this review, studies evaluating the efficacy of immunonutrition in cancer patients are summarized.https://dergipark.org.tr/tr/download/article-file/324280immunonutrientimmunonutritioncancer
spellingShingle Pelin Polat
M. Merve Tengillimoğlu Metin
Mevlüde Kızıl
Efficiency of Immunonutrition in Surgical Cancer Patients
Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi
immunonutrient
immunonutrition
cancer
title Efficiency of Immunonutrition in Surgical Cancer Patients
title_full Efficiency of Immunonutrition in Surgical Cancer Patients
title_fullStr Efficiency of Immunonutrition in Surgical Cancer Patients
title_full_unstemmed Efficiency of Immunonutrition in Surgical Cancer Patients
title_short Efficiency of Immunonutrition in Surgical Cancer Patients
title_sort efficiency of immunonutrition in surgical cancer patients
topic immunonutrient
immunonutrition
cancer
url https://dergipark.org.tr/tr/download/article-file/324280
work_keys_str_mv AT pelinpolat efficiencyofimmunonutritioninsurgicalcancerpatients
AT mmervetengillimoglumetin efficiencyofimmunonutritioninsurgicalcancerpatients
AT mevludekızıl efficiencyofimmunonutritioninsurgicalcancerpatients