Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents

Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents

Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl)furan-2-yl)methylene)hydrazinyl]-4-(4-fluorophenyl)thiazole and 2-[2-((5-(4-chloro-2-nitro...

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Bibliographic Details
Main Authors: Mehlika Dilek Altıntop, Ahmet Özdemir, Gülhan Turan-Zitouni, Sinem Ilgın, Özlem Atlı, Fatih Demirci, Zafer Asım Kaplancıklı
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
thiazole
hydrazone
furan
anticancer activity
anticandidal activity
Online Access:http://www.mdpi.com/1420-3049/19/9/14809

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