Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysis
AIM: To evaluate the efficacy and safety of ultrasound cycloplasty (UCP) for glaucoma. METHODS: A comprehensive search of PubMed, Embase, Web of Science, and Google Scholar databases was used to select studies met the inclusion criteria. Meta-analysis was performed by Review Manager and StataCorp LL...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2023-08-01
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| Series: | International Journal of Ophthalmology |
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| Online Access: | http://ies.ijo.cn/en_publish/2023/8/20230819.pdf |
| _version_ | 1797773026173911040 |
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| author | Tian-Hong Wu Xue Yin Jian-Qing Li Pei-Rong Lu |
| author_facet | Tian-Hong Wu Xue Yin Jian-Qing Li Pei-Rong Lu |
| author_sort | Tian-Hong Wu |
| collection | DOAJ |
| description | AIM: To evaluate the efficacy and safety of ultrasound cycloplasty (UCP) for glaucoma. METHODS: A comprehensive search of PubMed, Embase, Web of Science, and Google Scholar databases was used to select studies met the inclusion criteria. Meta-analysis was performed by Review Manager and StataCorp LLC. RESULTS: A total of 19 articles met the inclusion criteria. Overall, UCP is effective and safe in the glaucoma treatment, the risk ratio (RR) of the success rate was 2.28 (95%CI, 1.82-2.84). After UCP, patients had a significant reduction in intraocular pressure (IOP; mm Hg), the weighted mean difference (WMD) was 11.39 (95%CI, 9.88-12.90). In addition, UCP brings fewer postoperative complications with RR of 0.30 (95%CI, 0.19-0.49). Most of the complications were short-term and mild. Postoperatively, patients' use of IOP-lowering medications reduced, the standardized mean difference (SMD) was 0.78 (95%CI, 0.40-1.17). However, best corrected visual acuity (BCVA; logMAR) did not have obvious improvement after UCP, the WMD was 0.01 (95%CI, -0.06-0.09). This procedure does provide painfulness relief, with RR of 3.06 (95%CI, 1.95-4.81). CONCLUSION: UCP is effective and safe for suitable glaucoma. It can effectively decrease IOP in glaucoma patients, reduce the patients' dependence on IOP-lowering medications after surgery, relief the painfulness and has fewer long-term or severe postoperative complications, but the BCVA did not improve much. |
| first_indexed | 2024-03-12T22:00:17Z |
| format | Article |
| id | doaj.art-a685a40815a84283acc182b6dbb5e49e |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-03-12T22:00:17Z |
| publishDate | 2023-08-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-a685a40815a84283acc182b6dbb5e49e2023-07-25T08:32:35ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982023-08-011681317132510.18240/ijo.2023.08.1920230819Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysisTian-Hong Wu0Xue Yin1Jian-Qing Li2Pei-Rong Lu3Pei-Rong Lu. Department of Ophthalmology, the First Affiliated Hospital of Soochow University, Shizi Street 188, Suzhou 215006, Jiangsu Province, China. lupeirong@suda.edu.cnDepartment of Ophthalmology, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, ChinaAIM: To evaluate the efficacy and safety of ultrasound cycloplasty (UCP) for glaucoma. METHODS: A comprehensive search of PubMed, Embase, Web of Science, and Google Scholar databases was used to select studies met the inclusion criteria. Meta-analysis was performed by Review Manager and StataCorp LLC. RESULTS: A total of 19 articles met the inclusion criteria. Overall, UCP is effective and safe in the glaucoma treatment, the risk ratio (RR) of the success rate was 2.28 (95%CI, 1.82-2.84). After UCP, patients had a significant reduction in intraocular pressure (IOP; mm Hg), the weighted mean difference (WMD) was 11.39 (95%CI, 9.88-12.90). In addition, UCP brings fewer postoperative complications with RR of 0.30 (95%CI, 0.19-0.49). Most of the complications were short-term and mild. Postoperatively, patients' use of IOP-lowering medications reduced, the standardized mean difference (SMD) was 0.78 (95%CI, 0.40-1.17). However, best corrected visual acuity (BCVA; logMAR) did not have obvious improvement after UCP, the WMD was 0.01 (95%CI, -0.06-0.09). This procedure does provide painfulness relief, with RR of 3.06 (95%CI, 1.95-4.81). CONCLUSION: UCP is effective and safe for suitable glaucoma. It can effectively decrease IOP in glaucoma patients, reduce the patients' dependence on IOP-lowering medications after surgery, relief the painfulness and has fewer long-term or severe postoperative complications, but the BCVA did not improve much.http://ies.ijo.cn/en_publish/2023/8/20230819.pdfultrasound cycloplastyglaucomaefficacysafety |
| spellingShingle | Tian-Hong Wu Xue Yin Jian-Qing Li Pei-Rong Lu Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysis International Journal of Ophthalmology ultrasound cycloplasty glaucoma efficacy safety |
| title | Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysis |
| title_full | Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysis |
| title_fullStr | Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysis |
| title_full_unstemmed | Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysis |
| title_short | Efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma: a Meta-analysis |
| title_sort | efficacy and safety of ultrasound cycloplasty for the treatment of glaucoma a meta analysis |
| topic | ultrasound cycloplasty glaucoma efficacy safety |
| url | http://ies.ijo.cn/en_publish/2023/8/20230819.pdf |
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