Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant Escherichia coli ST131

Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant Escherichia coli ST131

ABSTRACT Urinary tract infections (UTIs) are one of the most common bacterial infections in humans, with ~400 million cases across the globe each year. Uropathogenic Escherichia coli (UPEC) is the major cause of UTI and increasingly associated with antibiotic resistance. This scenario has been worse...

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Bibliographic Details
Main Authors: Minh-Duy Phan, Horst Joachim Schirra, Nguyen Thi Khanh Nhu, Kate M. Peters, Sohinee Sarkar, Luke P. Allsopp, Maud E. S. Achard, Ulrike Kappler, Mark A. Schembri
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
uropathogenic Escherichia coli
urinary tract infection
bacterial pathogenesis
Online Access:https://journals.asm.org/doi/10.1128/mbio.03388-23

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